Results 111 to 120 of about 261,497 (358)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Effectiveness of a novel extraction method for semen: comparison using liquid samples and dried stains [PDF]

, 2016
Forensic analysis of deoxyribonucleic acid (DNA) collected from sexual assault evidence is a multi-step process that requires a great amount of time and resources.
Cassis, Patricia Rose
core   +1 more source

New Kunitz-Type HCRG Polypeptides from the Sea Anemone Heteractis crispa

Marine Drugs, 2015
Sea anemones are a rich source of Kunitz-type polypeptides that possess not only protease inhibitor activity, but also Kv channels toxicity, analgesic, antihistamine, and anti-inflammatory activities.
Irina Gladkikh, Margarita Monastyrnaya, Elena Zelepuga, Oksana Sintsova, Valentin Tabakmakher, Oksana Gnedenko, Alexis Ivanov, Kuo-Feng Hua, Emma Kozlovskaya   +8 more
doaj   +1 more source

Antibacterial action mechanisms and mode of trypsin inhibitors: a systematic review. [PDF]

J Enzyme Inhib Med Chem, 2022
de Souza Nascimento AM, de Oliveira Segundo VH, Felipe Camelo Aguiar AJ, Piuvezam G, Souza Passos T, Florentino da Silva Chaves Damasceno KSFDS, de Araújo Morais AH.   +6 more
europepmc   +1 more source

THE SITE OF INHIBITION OF BLOOD CLOTTING BY SOY BEAN TRYPSIN INHIBITOR 1 [PDF]

, 1951
Mary Beth Glendening, Ernest W. Page
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Proteomic analysis of the excretory-secretory products from larval stages of Ascaris suum reveals high abundance of glycosyl hydrolases [PDF]

, 2013
Background: Ascaris lumbricoides and Ascaris suum are socioeconomically important and widespread parasites of humans and pigs, respectively. The excretory-secretory (ES) molecules produced and presented at the parasite-host interface during the different
Deforce, Dieter, Dhaenens, Maarten, Gasser, Robin B, Geldhof, Peter, Jex, Aaron R, Van Steendam, Katleen, Vlaminck, Johnny, Wang, Tao   +7 more
core   +5 more sources

Avaliação biológica de soja com baixas atividades de inibidores de tripsina e ausência do inibidor Kunitz

Archivos Latinoamericanos de Nutrición, 2001
Cultivar de soja BR 36 com atividades de inibidores de tripsina convencional e linhagem BRM 95-5262, geneticamente modificadas para conter baixas atividades de inibidores de tripsina, contendo 40 e 20 e 30 e 20% de atividades residuais relativa de ...
Edna Mayumi Yuahasi Miura, Marco Aurélio R. Binotti, Daliane Souza de Camargo, Ivone Yurika Mizubuti, Elza Iouko Ida   +4 more
doaj  

Spiders' digestive system as a source of trypsin inhibitors: functional activity of a member of atracotoxin structural family. [PDF]

Sci Rep, 2023
Neto OBS, Valladão R, Coelho GR, Dias R, Pimenta DC, Lopes AR.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source