Results 131 to 140 of about 256,479 (340)

Wheat amylase/trypsin inhibitors (ATIs): occurrence, function and health aspects. [PDF]

open access: yesEur J Nutr, 2022
Geisslitz S   +14 more
europepmc   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

open access: yesAdvanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung   +8 more
wiley   +1 more source

Absolute and relative quantitation of amylase/trypsin-inhibitors by LC-MS/MS from wheat lines obtained by CRISPR-Cas9 and RNAi. [PDF]

open access: yesFront Plant Sci, 2022
Geisslitz S   +7 more
europepmc   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

open access: yesAdvanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar   +6 more
wiley   +1 more source

Genetic architecture underlying the expression of eight α-amylase trypsin inhibitors. [PDF]

open access: yesTheor Appl Genet, 2021
El Hassouni K   +8 more
europepmc   +1 more source

Development of Substrate‐Independent Antifouling and Bactericidal Surfaces Using Visible Light Cross‐Linked Hydrogel Coatings for Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
A new antifouling, antithrombogenic, and bactericidal hydrogel coating method is developed for implantable medical devices. The hydrogel coating can be easily formed by visible‐light crosslinking and is universally applicable to all substrates, ranging from polymers to metals.
Soonjong Roh   +4 more
wiley   +1 more source

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