Results 121 to 130 of about 6,474 (183)

Identification of altered blood metabolic pathways in equines following ethyl pyruvate administration using non-targeted metabolomics. [PDF]

Sci Rep
Kwak YB, Seo SA, Kim M, Yoon J.
europepmc   +1 more source

Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2. [PDF]

Sci Rep
Lotz-Jenne C, Lange R, Cren S, Bourquin G, Goglia L, Kimmerlin T, Wicki M, Müller M, Artico N, Ackerknecht S, Pfaff P, Joesch C, Mac Sweeney A.   +12 more
europepmc   +1 more source

Nootropic foods in neurodegenerative diseases: mechanisms, challenges, and future. [PDF]

Transl Neurodegener
Nguyen LAM, Simons CW, Thomas R.
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Gene Variant Frequencies of IDO1, IDO2, TDO, and KMO in Substance Use Disorder Cohorts. [PDF]

Genes (Basel)
Contella L, Farrell CL, Boccuto L, Litwin A, Snyder ML.   +4 more
europepmc   +1 more source

Ketogenic Diet and Gut Microbiota: Exploring New Perspectives on Cognition and Mood. [PDF]

Foods
Jiang Y, Chen Y, Chen Y, Gong X, Chen Z, Zhang X.   +5 more
europepmc   +1 more source

Indole-3-Lactic Acid Inhibits Doxorubicin-Induced Ferroptosis Through Activating Aryl Hydrocarbon Receptor/Nrf2 Signalling Pathway. [PDF]

J Cell Mol Med
Lian J, Lin H, Zhong Z, Song Y, Shao X, Zhou J, Xu L, Sun Z, Yang Y, Chi J, Wang P, Meng L.   +11 more
europepmc   +1 more source

CD103+ dendritic cell-fibroblast crosstalk via TLR9, TDO2, and AHR signaling drives lung fibrogenesis. [PDF]

JCI Insight
Carter H, Costa RM, Adams TS, Gilchrist TM, Emch CE, Bame M, Oldham JM, Huang SK, Linderholm AL, Noth I, Kaminski N, Moore BB, Gurczynski SJ.   +12 more
europepmc   +1 more source

5-methoxytryptophan ameliorates renal ischemia/reperfusion injury by alleviating endoplasmic reticulum stress-mediated apoptosis through the Nrf2/HO-1 pathway. [PDF]

Front Pharmacol
Li S, Yang H, Zhang B, Li L, Li X.
europepmc   +1 more source

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The activation of the enzyme tryptophan oxygenase

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971
Abstract 1. 1. The activation of the liver enzyme tryptophan oxygenase has been studied in the frog and rat. 2. 2. Hematin, an iron protoporphyrin, activates the rat enzyme but has no effect on the frog enzyme. 3. 3. Microsomes and mitochondria from both species contain an activator(s) distinct from hematin which is effective in both rat ...
Neal A. Rubinstein, Melvin Spiegel, Evelyn Spiegel   +2 more
openaire   +3 more sources

Tryptophan uptake and tryptophan oxygenase activity in mice

Biochemical and Biophysical Research Communications, 1970
Abstract Groups of mice were injected intraperitoneally with L-tryptophan, 1 mg/gm body weight, and maintained at room temperature (22° C) or exposed to acute heat stress (36° C). In the heat-stressed animals, plasma tryptophan levels were lower at each time interval studied when compared with room temperature controls; however, both hepatic ...
Ralph P. Francesconi, Milton Mager
openaire   +3 more sources