Results 131 to 140 of about 87,880 (172)

Single-wavelength spectrophotometric assay for tryptophan oxygenase

Analytical Biochemistry, 1977
Abstract The activity of the enzyme tryptophan oxygenase is determined by a simple sensitive single-wavelength spectrophotometric assay of the rate of formation of two rapidly formed products, N-formylkynurenine and kynurenine. The sum of the concentrations of both products is determined at the wavelength of their isosbestic point, 337 nm, where for ...
J A, Symanski, D A, Bennett
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A specific and sensitive fluorometric assay for tryptophan oxygenase

Archives of Biochemistry and Biophysics, 1973
Abstract A spectrophotofluorometric assay was used to measure tryptophan oxygenase activity in several species. The fluorescent assay depends on the conversion of the product of the reaction, N-formyl- l -kynurenine, to anthranilate by means of the coupling enzymes kynurenine formamidase and kynureninase.
D A, Casciano, F H, Gaertner
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Activation of liver tryptophan oxygenase by hydrocortisone, hematin and tryptophan in streptozotocin-diabetic rats

Life Sciences, 1984
This study compared changes in liver tryptophan oxygenase (TPO) activity in response to hydrocortisone, hematin and tryptophan administration to non-diabetic and diabetic (streptozotocin) rats. Hydrocortisone caused similar increases in apoenzyme (inactive), holoenzyme (heme-saturated) and total (holoenzyme + apoenzyme) TPO activities in non-diabetic ...
E M, Sadler, M, Weiner, G G, Buterbaugh
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Tryptophan, Oxygenase, and Sleep

1996
In May 1974, or about 21 years ago, when the first International Meeting of ISTRY was held in this beautiful city of Padova, I had the great pleasure of making personal acquaintance with Prof. Luigi Musajo, whom I had heard about so much while I was in Japan.
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Dexamethasone control of the development of tryptophan oxygenase in young rats

Life Sciences, 1981
Abstract Tryptophan 2, 3-dioxygenase activity follows a characteristic pattern of change during development of suckling rats; namely, it is appears 2 weeks after birth and then increases to the adult level by day 22. Glucocorticoids, potent inducers of the enzyme in adult rats, can induce its precocious appearance on day 8 or 10 after birth (1) or ...
T, Hirota, S, Yoshikazu, T, Tanaka
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The effect of ethyl alcohol on rat liver tryptophan oxygenase

Life Sciences, 1972
Abstract The activity of liver tryptophan oxygenase was determined in rats administered intoxicating dose of ethanol. Following intraperitoneal injection of ethanol there was a rise in the enzyme activity reaching levels considerably above those of the control animals.
V M, Sardesai, H S, Provido
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11–Deoxycortisol Induces Hepatic Tryptophan Oxygenase in Rats

Acta Pharmacologica et Toxicologica, 1985
Abstract: 11–Deoxycortisol (cortexolone) has previously been used as a glucocorticoid antagonist in vitro and in adrenalectomized rats. Antiglucocorticoid properties of 11–deoxycortisol in intact rats were examined by studying the effect of 11–deoxycortisol on the induction of hepatic tryptophan oxygenase (TO) by corticosterone.
H, Gjerde, G, Gadeholt, H, Olsen, J, Mørland, N, Norman   +4 more
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Studies on the allosteric regulation of tryptophan oxygenase structure and function

Advances in Enzyme Regulation, 1969
Abstract Tryptophan oxygenase activity in mammalian and microbial systems is subject to several interesting types of regulation. These include control of its rate of biogenesis and degradation which determine the in vivo level of enzyme protein; furthermore, an allosteric regulation exists which modulates the catalytic efficiency of these enzyme ...
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Tryptophan and α-methyltryptophan facilitation in the interaction of cyanide with tryptophan oxygenase

Biochemistry, 1968
H, Maeno, P, Feigelson
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Glucocorticoid induction of tryptophan oxygenase

Biochemical Pharmacology, 1983
C.Anthony Altar, Bennie L. Bennett, Ray Wallace, Arthur Yuwiler   +3 more
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