U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott +18 more
wiley +1 more source
Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]
Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K +7 more
core +1 more source
ABSTRACT Approaches integrating geospatial “big data” and machine learning will likely be increasingly used to predict conservation‐related human behavior, such as patterns of local engagement, in socioecological systems. Yet, few studies evaluate both the technical and ethical aspects of such applications.
Thomas Pienkowski +8 more
wiley +1 more source
Introduction Tsetse flies (Glossina) transmit Trypanosoma brucei gambiense, which causes gambiense human African trypanosomiasis (gHAT). As part of national efforts to eliminate gHAT as a public health problem, Uganda implemented a large-scale programme ...
Sophie Dunkley +10 more
doaj +1 more source
Insights from quantitative and mathematical modelling on the proposed 2030 goal for gambiense human African trypanosomiasis (gHAT) [PDF]
Gambiense human African trypanosomiasis (gHAT) is a parasitic, vector-borne neglected tropical disease that has historically affected populations across West and Central Africa and can result in death if untreated.
Aliee, Maryam +10 more
core +1 more source
Gonadulin and Insulin‐Like Growth Factor Involved in Rhipicephalus microplus Reproduction
Insulin‐like growth factor (IGF2) in ovaries of Rhipicephalus microplus partially engorged females. Ovaries from females at different feeding stages were used to detect IGF2. ABSTRACT Gonadulin and insulin‐like growth factor (IGF) are neuropeptides synthesized by the central nervous system (CNS) of arthropods.
Jéssica Waldman +8 more
wiley +1 more source
FITCA-EMMC workshops on information exchange and training with rural communities on environment: Eastern Uganda. W1 [PDF]
Four workshops were held in four sub counties in the districts of Soroti, Tororo, Iganga and Kamuli. Five to seven villages were involved in each sub county.
Kang'Ethe, Erastus +4 more
core
Temporal and spatial epidemiology of sleeping sickness and use of geographical information system (GIS) in Kenya [PDF]
Background & objectives: In Kenya, sleeping sickness (SS) caused by Trypanosoma brucei rhodesiense is confined to the Nyanza and Western Provinces tsetse belts.
Jane Jemeli Rutto, Julia Wairimu Karuga
doaj
The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda.
BACKGROUND: Sleeping sickness, caused by two trypanosome subspecies, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, is a parasitic disease transmitted by the tsetse fly in sub-Saharan Africa.
Coleman, PG +5 more
core +1 more source
Molecular epidemiology of African sleeping sickness [PDF]
Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT +5 more
core +2 more sources

