Results 31 to 40 of about 66,762 (307)

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Utility of the interferon-gamma release assay for latent tuberculosis infection screening among indian health-care workers

Indian Journal of Community Medicine, 2021
Background: The utility of interferon-gamma release assays (IGRAs) for latent tuberculosis infection (LTBI) screening among health-care workers (HCWs) in low- and middle-income countries (LMICs) remains unclear.
Sunita Girish, Aarti Kinikar, Geeta Pardesh, Sangita Shelke, Anita Basavaraj, Ajay Chandanwale, Dileep Kadam, Samir Josh, Gauri Dhumal, Nilima Lokhande, Andrea Deluca, Nikhil Gupte, Amita Gupta, Robert C Bollinger, Vidya Mave   +14 more
doaj   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Value of the tuberculin skin testing and of an interferon-gamma release assay in haemodialysis patients after exposure to M. tuberculosis

BMC Infectious Diseases, 2012
Background Patients with end-stage renal disease (ESRD) and Mycobacterium tuberculosis infection pose a high risk of developing active TB disease. It is therefore important to detect latent TB infection (LTBI) to be able to offer treatment and prevent ...
Anibarro Luis, Trigo Matilde, Feijoó Diana, Ríos Mónica, Palomares Luisa, Pena Alberto, Núñez Marta, Villaverde Carlos, González-Fernández África   +8 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Evaluation of the tuberculin skin test and the interferon-γ release assay for TB screening in French healthcare workers

Journal of Occupational Medicine and Toxicology, 2009
Introduction Using French cut-offs for the Tuberculin Skin Test (TST), results of the TST were compared with the results of an Interferon-γ Release Assay (IGRA) in Healthcare Workers (HCW) after contact to AFB-positive TB patients.
Raffi Francois, Houdebine Marietherese, Guillaumin Guyonne, Gordeeff Claire, Durand-Perdriel Marie-Henriette, Bourrut-Lacouture Martine, Muller Jean-Yves, Naudin Frederique, Germaud Patrick, Chailleux Edmond, Audrain Marie, Nael Virginie, Brunet-Courtois Benedicte, Tripodi Dominique, Boutoille David, Biron Charlotte, Potel Gilles, Roedlich Claude, Geraut Christian, Schablon Anja, Nienhaus Albert   +20 more
doaj   +1 more source

The Interoperability Challenge in DFT Workflows Across Implementations

Advanced Intelligent Discovery, EarlyView.
Interoperability and cross‐validation remain major challenges in the computational materials science. In this work, we introduce a common input/output standard that enables internal translation across multiple workflow managers—AiiDA, PerQueue, Pipeline Pilot, and SimStack—while producing results in a unified schema.
Simon K. Steensen, Tushar Singh Thakur, Manuel Dillenz, Johan M. Carlsson, Celso R. C. Rêgo, Eibar Flores, Hamidreza Hajiyani, Felix Hanke, Juan María García Lastra, Wolfgang Wenzel, Nicola Marzari, Tejs Vegge, Giovanni Pizzi, Ivano E. Castelli   +13 more
wiley   +1 more source

TÉCNICAS DE GEOPROCESSAMENTO APLICADAS PARA ANÁLISE TEMPORAL DO MICROCLIMA NA BACIA HIDROGRÁFICA DO CÓRREGO DO PEQUIÁ, MARANHÃO

Boletim Goiano de Geografia
A supressão da vegetação, o incremento das atividades antrópicas sem as medidas de mitigação necessárias e as alterações climáticas ocorridas ao longo dos anos têm sido importantes indicadores da degradação ambiental, implicando diretamente na qualidade ...
Felipe Alexandre Rizzo, Arthur Santos, Darllan Collins da Cunha e Silva   +2 more
doaj   +1 more source

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding, Dylan Hamitouche, Simon Thebault, Patrick Kearns, Ahmed Abdelhak, Adil Harroud   +5 more
wiley   +1 more source

MODELI NG CLINICAL AND ECONOMIC OUTCOMES OF TESTING FOR LTBI WITH T-SPOT.TB IN IMMUNOCOMPROMISED CHILDREN

Фармакоэкономика, 2015
weakening of immune status under the influence of some diseases or types of treatment could result in the activation of the present latent tuberculosis infection (LTBI).
V. I. Ignatyeva, M. V. Avxentyeva, V. V. Omelyanovsky, G. R. Khachatryan   +3 more
doaj