Results 41 to 50 of about 6,969 (204)

Clinical deterioration in community acquired infections associated with lymphocyte upsurge in immunocompetent hosts [PDF]

, 2004
Clinical deterioration during the course of community-acquired infections can occur as a result of an exaggerated immune response of the host towards the inciting pathogens, leading to immune-mediated tissue damage.
Cheng, VCC, Hung, IFN, Lau, SKP, Lee, RA, Tang, BSF, Woo, PCY, Wu, AKL, Yuen, KY   +7 more
core   +1 more source

Molecular characterization of Orientia tsutsugamushi causing scrub typhus among febrile patients in north-central Bangladesh

New Microbes and New Infections, 2019
Scrub typhus is a mite-borne rickettsial disease caused by Orientia tsutsugamushi, which is endemic in Asia Pacific region. In this study, infection rate and molecular epidemiologic traits of O.
M.M. Al Amin, S.K. Paul, M.S. Aung, A. Paul, M.A. Aziz, N.A. Khan, A.K.M.F. Haque, F. Ahamed, A. Melan, S.R. Sarker, M.A. Hossain, S. Ahmed, S.A. Nasreen, N. Haque, N. Kobayashi   +14 more
doaj   +1 more source

Continuous positive airway pressure (CPAP) to treat respiratory distress in newborns in low- and middle-income countries. [PDF]

, 2016
Severe respiratory distress is a serious complication common to the three major causes of neonatal mortality and morbidity (prematurity, intra-partum-related hypoxia and infections).
Ho JJ, Juan Emmanuel Dewez, Nynke van den Broek, World Bank   +3 more
core   +3 more sources

An outbreak investigation of scrub typhus in Nepal: confirmation of local transmission

BMC Infectious Diseases, 2021
Background Scrub typhus is a largely ignored tropical disease and a leading cause of undifferentiated febrile illness in the areas of tsutsugamushi triangle caused by Orientia tsutsugamushi.
Meghnath Dhimal, Shyam Prakash Dumre, Guna Nidhi Sharma, Pratik Khanal, Kamal Ranabhat, Lalan Prasad Shah, Bibek Kumar Lal, Runa Jha, Bishnu Prasad Upadhyaya, Bhim Acharya, Sanjaya Kumar Shrestha, Silas A. Davidson, Piyada Charoensinphon, Khem B. Karki   +13 more
doaj   +1 more source

Dual-Antigen Subunit Vaccine Nanoparticles for Scrub Typhus

Pathogens, 2023
Orientia tsutsugamushi is the causative pathogen of scrub typhus, an acute febrile disease prevalent in the Asia–Pacific region that is spread to people through chigger bites. Despite the emerging threat, there is no currently available vaccine against O.
Jaeyoung Park, Zhiwen Zhang, Tatyana Belinskaya, Alexandra N. Tsoras, Chien-Chung Chao, Le Jiang, Julie A. Champion   +6 more
doaj   +1 more source

Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study [PDF]

, 2017
Background Improved understanding of pathogens that cause sepsis would aid management and antimicrobial selection. In this study, we aimed to identify the causative pathogens of sepsis in southeast Asia.
Southeast Asia, Infectious
core  

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi.

PLoS Neglected Tropical Diseases
Scrub typhus is caused by Orientia tsutsugamushi infection and occurs frequently in an area called the Tsutsugamushi Triangle. Currently, there is no vaccine for O. tsutsugamushi, and its infection is treated with antibiotics such as doxycycline.
Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song   +11 more
doaj   +1 more source

Differences in clinical features according to Boryoung and Karp genotypes of Orientia tsutsugamushi.

PLoS ONE, 2011
BackgroundScrub typhus is an infectious disease caused by Orientia tsutsugamushi. The differences in virulence of O. tsutsugamushi prototypes in humans are still unknown.
Dong-Min Kim, Na Ra Yun, Ganesh Prasad Neupane, Sung Heui Shin, So Yeon Ryu, Hee Jung Yoon, Seong Heon Wie, Woo Jin Kim, Chang Youl Lee, Jong Soo Choi, Tae Young Yang   +10 more
doaj   +1 more source

Scrub Typhus Pathogenesis: Innate Immune Response and Lung Injury During Orientia tsutsugamushi Infection

Frontiers in Microbiology, 2019
Scrub typhus is an understudied, potentially lethal disease caused by infection with Orientia tsutsugamushi. Despite causing an estimated 1 million cases per year and an increasing global presence, mechanisms of scrub typhus pathogenesis remain unclear ...
Brandon Trent, James Fisher, Lynn Soong, Lynn Soong   +3 more
doaj   +1 more source