Results 151 to 160 of about 9,079 (311)

Advanced Mounting Technique for Improved Imaging and Analysis of Embedded Spheroids and Migrating Cells in Light Sheet Fluorescence Microscopy

open access: yesAdvanced Materials Technologies, EarlyView.
A novel sample holder compatible with the Zeiss Lightsheet 7 microscope improves imaging of spheroids embedded in collagen matrices. By enabling dual‐sided illumination, it enhances image quality and quantitative analysis of migrating cells. This method advances 3D light sheet microscopy for studying tumor invasion and therapeutic responses.
Masoumeh Mohamadian Namaqi   +5 more
wiley   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

open access: yesAdvanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees   +5 more
wiley   +1 more source

Fabrication Technologies for Soft, Multimaterial Optical Fibers for In Vivo Diagnostics and Phototherapy, With a Focus on Extrusion Printing

open access: yesAdvanced Materials Technologies, EarlyView.
Soft multimaterial optical fibers integrate multiple functionalities—such as waveguiding, side emission, sensing, drug delivery or actuation—into a single filament for wearable, implantable, and tissue‐integrated devices for diagnostics and phototherapy.
Zahra Kafrashian   +2 more
wiley   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

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