Results 61 to 70 of about 146,644 (262)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Simple and Efficient Technique for Correction of Unilateral Scissor Bite Using Straight Wire- A Correspondence [PDF]

Journal of Clinical and Diagnostic Research, 2020
Pranshu Mathur, Parijat Chakraborty, Richa Dhingra, Roli Dureha, Priyanka Singh   +4 more
doaj   +1 more source

Investigation of mechanical and metallurgical properties of commercially pure titanium grade 2 tube-to-tubesheet joints

Scientific Reports
The present study investigated the structural integrity of three categories of Titanium Grade 2 based tube and tubesheet joints manufactured using welding, roller expansion and hybrid welding cum roller expansion process, to evaluate their mechanical ...
Ahmad Al Tamimi, Dinu Thomas Thekkuden, Abdel-Hamid Ismail Mourad, Mohammad Alkhedher   +3 more
doaj   +1 more source

The Expansion Mode of Adult Matsucoccus Matsumurae (Hemiptera: Margarodidae) in Pinus Thunbergii (Pinales: Pinaceae) and Pinus Densiflora (Pinales: Pinaceae) Forests in Shandong Province, China [PDF]

E3S Web of Conferences
Understanding the expansion mode of adult Matsucoccus matsumurae Kuwana (Hemiptera: Margarodidae) is important for pest control and management measures. The infection situation, emergence patterns, host selection and aggregation behaviors of females have
Gao Xing, Chen MengJiao, Zhang Ranran, Qiu Hong, Dai Lulu, Zhao Mingzhen   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

RESEARCH ON THE ENERGY ABSORPTION CHARACTERISTICS OF EXPANSION TUBE ENERGY ABSORBING ELEMENTS FOR RAIL VEHICLES

Jixie qiangdu, 2019
In this paper, the expansion tube type energy absorbing element was taken as the research object, and 9 samples were tested by automatic electro-hydraulic servo press and large drop hammer impact tester.
HE ShiZhong, HUANG Ke
doaj  

Stress Concentration Factor of Expanded Aluminum Tubes Using Finite Element Modeling

The Journal of Engineering Research, 2013
This paper discusses the development of semi-empirical relations for the maximum stress concentration factor (SCF) around circular holes embedded in aluminum tubes under various expansion ratios and mandrel angles. Finite element models were developed to
L Mhamdi, AC Seibi, A Karrech, S El-Borgi, I Barsoum   +4 more
doaj   +1 more source