Results 201 to 210 of about 75,244 (265)

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Interaction between reflected shock waves and laser-induced cavitation bubbles. [PDF]

Ultrason Sonochem
Dawoodian M, Rezaee S, Barman D, El Moctar O, Sainz RM, Mettin R, Lechner C.   +6 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Experimental Investigation of the directional collapse and microjet dynamics of single acoustic bubbles in confined tubes. [PDF]

Ultrason Sonochem
Wu H, Zhang T, Fang Y, Yu R, Jin Y, Ohl CD, Li Y.   +6 more
europepmc   +1 more source

Bioinspired milliscale near-boundary undulatory motion for fluid transport and adhesive locomotion. [PDF]

Sci Adv
Liu S, Zheng Y, Zhu K, Li X, Zhang R, Ma K, Guan J, Sitti M, Wen L, Ren Z.   +9 more
europepmc   +1 more source

Flexible Sensorized Tube for Pipeline Defect Detection Based on Bending and Pressure Sensing. [PDF]

Sensors (Basel)
Chen Y, Chen H, Yin Y, Chen J, Lu B, Chen T, Zhu M.   +6 more
europepmc   +1 more source

Visualization of Swirling Flow in a 3-dimensional Helical Stent Model using Color-coded Circulation and 4-dimensional Flow Magnetic Resonance Imaging. [PDF]

Interv Radiol (Higashimatsuyama)
Maruyama M, Kawasumi T, Kimura Y, Aso H, Kaneko K, Sasaki S, Ohta M.   +6 more
europepmc   +1 more source

Anatomical and Histological Characterization of the Intestine of Artibeus lituratus. [PDF]

Anat Histol Embryol
de Oliveira Magalhães M, da Rocha JHL, de Sousa Verde R, de Oliveira Aquino M, Amorim JM, da Silva TIB, de Araújo Santos FG.   +6 more
europepmc   +1 more source

Comparative assessment of floral bud morphological differences among three eucalyptus species and their potential relationship on hybrid pollination. [PDF]

BMC Plant Biol
Liu X, Ou Y, Su Z, Ouyang T, Quiñónez-Barraza G, Wang C.   +5 more
europepmc   +1 more source

Bending behaviour of thick-walled composite tubes

openaire   +1 more source