Results 161 to 170 of about 269,521 (336)

Tuberous Sclerosis Complex

open access: yesThe Keio Journal of Medicine
Tuberous sclerosis complex (TSC) is an autosomal dominant inherited disease characterized by systemic hamartomas, neuropsychiatric symptoms known as TAND (TSC-associated neuropsychiatric disorders), and vitiligo. These symptoms are attributed to the constant activation of mechanistic target of rapamycin complex 1 (mTORC1) caused by genetic mutations in
openaire   +3 more sources

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen   +6 more
wiley   +1 more source

PERFORMANCE OF ACID-ADAPTIVE SOYBEAN EXPECTED LINES IN SOUTH LAMPUNG, INDONESIA

open access: yesAGRIVITA Journal of Agricultural Science, 2014
Acid soil area is one of the areas broadly available in Indonesia. However, the complexity of acid soil may lead to low soybean productivity. Hence, soybean variety which is adaptive to acid soil is needed.
Heru Kuswantoro   +7 more
doaj  

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F‐box domain

open access: yesEpilepsia Open, EarlyView.
Abstract The FBXW7 gene encodes a substrate‐recognition component of the Skp1‐Cul1‐F‐box (SCF) E3 ubiquitin ligase complex, which targets key regulatory proteins for proteasomal degradation. Recently, loss‐of‐function FBXW7 variants have been associated with a novel neurodevelopmental disorder characterized by heterogeneous clinical features.
Anees Muhammad   +10 more
wiley   +1 more source

Diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition to adult care: A retrospective cohort study in a tertiary epilepsy center

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition period to adult care at a tertiary epilepsy center. Methods We conducted a retrospective cohort study of 317 patients previously diagnosed with childhood ...
Tetsuhiro Fukuyama   +9 more
wiley   +1 more source

Validation of a handheld smartphone markerless gait‐analysis tool using an estimated groundline in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background A handheld smartphone‐based computer vision algorithm (RealHorse® [RH]) offers accessible alternatives for equine gait analysis but requires validation against a gold‐standard three‐dimensional multicamera optical motion capture system (Qualisys® [QS]).
Karsten Key   +4 more
wiley   +1 more source

The Resistance of Soybean Genotypes to The Pod Feeding Insects

open access: yesPlanta Tropika: Jurnal Agrosains, 2019
One of the constraints impeding soybean production in the tropics is yield losses due to the damage by pod feeding insects. The research objective was to identify the resistance of soybean genotypes to the pod feeders.
Ayda Krisnawati, Mochammad Muchlish Adie
doaj  

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska   +6 more
wiley   +1 more source

Chemistry Composition and Bioaccessibility Study of Phenolic Compounds and Carotenoids of New Brazilian Biofortified Sweet Potato “CIP BRS Nuti”

open access: yesFood Chemistry International, EarlyView.
Phenolic compounds of sweet potato CIP BRS Nuti were evaluated for the first time. Catechin, epicatechin, and procyanidin B1 exhibited high bioaccessibility. ABSTRACT Sweet potatoes biofortified in carotenoids have been an alternative to combat malnutrition in vulnerable populations. This work is the first comprehensive study of the bioactive potential
Maria Carla Cândido da Silva   +7 more
wiley   +1 more source

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