Results 31 to 40 of about 67,344 (261)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Diversity in Tuber Characteristics of Local Cultivars of Yam Bean (Pachyrhizus erosus) in Indonesia

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2018
Yam bean is legume with tuberous root originated from the semiarid tropics of Central America, and has been widely spread in several regions in Indonesia.
Ayda Krisnawati   +2 more
doaj   +1 more source

Drip fertigation for greater yam (Dioscorea alata) and maize (Zea mays) intercropping

open access: yesThe Indian Journal of Agricultural Sciences, 2021
An experiment was laid out in split-plot design with three replications. Main and sub plots consisted of drip irrigation [I1- at 80% of cumulative pan evaporation (CPE) during 1-270 days after planting (DAP), I2-at 100% of CPE during 1-90 DAP + at 80 ...
M NEDUNCHEZHIYAN, G BYJU, S K JATA
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Evaluation of Promising Sweet potato Clones for Higher Root Yield and Dry Matter Content

open access: yesPlanta Tropika: Jurnal Agrosains, 2021
Dry matter content is one of the important characteristics of sweet potatoes in addition to high yield. The aim of this study was to evaluate the performance of promising sweet potato clones for higher root yield and dry matter content.
Wiwit Rahajeng   +3 more
doaj   +1 more source

Tuberous sclerosis

open access: yesDermatology Online Journal, 2008
A 46-year-old woman presented with multiple, skin-colored, hyperpigmented, dome-shaped facial papules. Histopathologic examination was consistent with angiofibromas. Clinical history and examination were consistent with tuberous sclerosis. The clinical manifestations, pathogenesis, evaluation, and treatment of tuberous sclerosis are discussed.
Wee, Sue Ann, Fangman, Bill
openaire   +4 more sources

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

open access: yesAdvanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena   +7 more
wiley   +1 more source

Projected changes in mean temperature and total precipitation and climate suitability of cassava (Manihot esculenta) in major growing environments of India

open access: yesThe Indian Journal of Agricultural Sciences, 2016
Cassava (Manihot esculenta Crantz) is an important food crop of India cultivated in an area of 228 000 ha for food, feed and fuel, contributes to food security, equity, poverty alleviation and environmental protection.
SABITHA SOMAN, G BYJU, J SREEKUMAR
doaj   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

open access: yesAdvanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

GGE Biplot Analysis of Multi-Environment Yield Trials in Soybean Promising Lines

open access: yesIlmu Pertanian (Agricultural Science), 2019
Soybean in Indonesia is grown in diverse agro-ecological environments. The performance of soybean yield often varies due to significant genotype × environment interaction (GEI), therefore the yield stability of performance is an important consideration ...
Ayda Krisnawati, M. Muchlish Adie
doaj   +1 more source

Home - About - Disclaimer - Privacy