Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling [PDF]
Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with
Andrews, Paul S. +8 more
core +5 more sources
Adverse reactions of biological therapies in patients with psoriasis [PDF]
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R. +5 more
core +4 more sources
Hepatic tuberculosis: myriad of hues
Gastrointestinal tuberculosis is an important form of extrapulmonary tuberculosis but liver involvement is uncommon. Hepatic tuberculosis can manifest in variable manners including as a space occupying lesion, diffuse infiltration by granulomas (granulomatous hepatitis) and as liver abscess.
Arup, Choudhury +5 more
openaire +3 more sources
Introduction Isolated hepatic tuberculosis is an uncommon manifestation of one of the most common infections worldwide, caused by Mycobacterium tuberculosis. Extremely high serum ferritin, which is regarded as a marker of adult onset Still’s disease, has
Manoj Edirisooriya +2 more
doaj +1 more source
The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]
Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E +7 more
core +1 more source
A Diagnostic Dilemma: Isolated Hepatic Tuberculosis as A Rare And Unusual Presentation of TB
Tuberculosis (TB) is the major problem being faced worldwide, particularly in developing countries, and therefore, it is important to recognize the unusual presentations of the disease.
Aamer Ubaid +2 more
doaj +1 more source
Polyarteritis Nodosa – Risk of Stopping Immunosuppressent and a Rare Fatal Complication [PDF]
Background: Polyarteritis nodosa (PAN) is a systemic necrotising vasculitis which can cause multifocal aneurysms of visceral arteries, which may rupture causing haemorrhage, thrombosis, organ ischemia and infarction While the treatment of vasculitis ...
Akhil PAUL +2 more
doaj +1 more source
Primary hepatic tuberculosis is a rare presentation and sporadically reported in the literature, mostly from our part of the world. Sometimes the presentation can be atypical and mimics hepatic tumor and poses diagnostic challenge.
Muhammad Manzoor Ul Haque +3 more
doaj +1 more source
p53 positively regulates the proliferation of hepatic progenitor cells promoted by laminin-521
Hepatic progenitor cells (HPCs) hold tremendous potential for liver regeneration, but their well-known limitation of proliferation hampers their broader use.
Mingyang Ma +9 more
doaj +1 more source
Nevirapine versus Efavirenz for patients co-infected with HIV and Tuberculosis: A Randomised Non-Inferiority Trial [PDF]
BACKGROUND: In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-
Agnès Sobry +39 more
core +3 more sources

