Results 71 to 80 of about 70,273 (250)

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Case report on serohepatic tuberculosis (frosted liver): Clinical presentation, imaging, diagnosis, and management

Radiology Case Reports
Hepatic tuberculosis can manifest in various forms, including parenchymal, serohepatic, tuberculous cholangitis and mixed form. Isolated hepatic tuberculosis, specifically in the form of serohepatic tuberculosis, is very rare.
Prajwal Dahal, MD, Alina Awale, MD, Sabina Parajuli, MBBS   +2 more
doaj   +1 more source

Nevirapine- and efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique. [PDF]

, 2012
To describe the frequency, risk factors, and clinical signs and symptoms associated with hepatotoxicity (HT) in patients on nevirapine- or efavirenz-based antiretroviral therapy (ART), we conducted a retrospective cohort analysis of patients attending ...
Biot, M, Chu, K M, Ford, N P, Manzi, M, Rasschaert, F, Zachariah, R, Zuniga, I   +6 more
core   +2 more sources

Diagnostic Performance of Comprehensive Point‐of‐Care Ultrasound for Pediatric Tuberculosis in Spain: A Prospective Observational Study

Journal of Clinical Ultrasound, EarlyView.
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju, Antoni Noguera‐Julian, Aleix Soler‐Garcia, Antoni Soriano‐Arandes, José Miguel Escudero Fernández, Maria Espiau, Begoña Santiago Garcia, Alicia Hernanz‐Lobo, Ángel M. Lancharro Zapata, Enrique Ladera, Angela Manzanares, Daniel Blazquez, Elisa Aguirre Pascual, Isabelle Thierry‐Chef, Danilo Buonsenso, Xavier Serres‐Créixams, Quique Bassat, Elisa Lopez‐Varela   +17 more
wiley   +1 more source

Detection of Mycobacterium tuberculosis in a patient with suspected cystic echinococcosis: a case report

Journal of Medical Case Reports
Background Tuberculosis is a global health issue affecting millions of people worldwide. While pulmonary tuberculosis is common, hepatic tuberculosis is rare and accounts for less than 1% of cases.
Simon Daller, Julian Frederic Hotz, Moritz Staudacher, Polina Kalinina, Susanna Lang, Fredrik Waneck, Heimo Lagler   +6 more
doaj   +1 more source

Iron Regulation in Elderly Asian Elephants (Elephas maximus) Chronically Infected With Mycobacterium tuberculosis

Frontiers in Veterinary Science, 2020
Restriction of nutrients to pathogens (nutritional immunity) is a critical innate immune response mechanism that operates when pathogens such as Mycobacterium tuberculosis have the potential to evade humoral immunity.
Maja Ruetten, Hanspeter W. Steinmetz, Markus Thiersch, Marja Kik, Lloyd Vaughan, Sandro Altamura, Martina U. Muckenthaler, Martina U. Muckenthaler, Martina U. Muckenthaler, Max Gassmann, Max Gassmann   +10 more
doaj   +1 more source

Epitheloid Variant of Angiomyolipoma in a Patient with Tuberous Sclerosis. [PDF]

, 2013
Epitheloid angiomyolipoma of kidney is a type of Perivascular endothelial cell derived tumor with an aggressive behaviour with specific pathological, immunohistochemistrical and genetic characteristics.
Amirtham, U, Challa, VR, Goud, BYG, Rangappa, P, Swamyvelu, K   +4 more
core   +1 more source

Editorial:Metformin: Beyond Diabetes [PDF]

, 2019
International ...
Bost, Canto, El-Mir, Evans, Ferreira, Foretz, Foretz, Forslund, Hawley, Kaminski, Leung, Madiraju, Martin-Montalvo, Mohan, Neumann, Owen, Patel, Rena, Saxton, Zhou   +19 more
core   +4 more sources

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

Journal of Clinical Ultrasound, EarlyView.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C, Chajek-Shaul T, Engelmann H, Ettinger WH, Ettinger WH, Ettinger WH, Feingold KR, Feingold KR, Flegel WA, Gouni I, Graham A, Greenberg AS, Grove RI, Grunfeld C, Hubsch AP, Ishibashi S, Kipp HA, Moran CS, Netea MG, Pacelli F, Pak YK, Read TE, Semb H, Stopeck AT, Van Gameren MM, Weinstock C, Wilson DE, Yokoyama K   +27 more
core   +1 more source