INTRODUCTION: Gene-Xpert MTB RIF (Xpert) is based on nucleic acid amplification by real-time polymerase chain reaction, which allows for the identification of Mycobacterium tuberculosis and rifampin resistance.
Rafaela Baroni Aurilio +4 more
doaj +1 more source
Acid fast staining in formalin-fixed tissue specimen of patients with extrapulmonary tuberculosis [PDF]
Diagnosis of extrapulmonary tuberculosis (EPTB) is difficult owing to low number of bacilli in the specimens, lack of adequate sample and non-uniform distribution of bacteria in tissues.
Azarhoush, R. +3 more
core
An unusual unifocal presentation of Castleman’s disease in a young woman with a detailed description of sonographic findings to reduce diagnostic uncertainty: a case report [PDF]
Background: Castleman’s disease is a rare lymphoproliferative disorder. It typically presents as mediastinal masses and causes a wide range of clinical symptoms.
Maden, Zerrin, Wagner, Norbert
core +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Diagnostic value of tuberculosis-specific antigens ESAT-6 and CFP10 in lymph node tuberculosis
Objective: To assess the diagnostic value of immunohistochemical (IHC) staining for detecting the tuberculosis-secreted antigens ESAT-6 and CFP10 in lymph node tuberculosis.
Xueqian Chen +6 more
doaj +1 more source
Diagnostic Role of Lymphnode Imprint: A Cyto-histopathological Correlation
Introduction: Lymphadenopathy is a very common condition for which excision biopsy is often recommended when fine needle aspiration cytology is not conclusive. Lymph node imprint cytology is a useful and rapid alternative diagnostic tool.
Prabesh Kumar Choudhary +3 more
doaj +1 more source
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel +53 more
core +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Interleukin-17 is required for control of chronic lung infection caused by Pseudomonas aeruginosa [PDF]
Chronic pulmonary infection with Pseudomonas aeruginosa is a feature of cystic fibrosis (CF) and other chronic lung diseases. Cytokines of the IL-17 family have been proposed as important in the host response to P. aeruginosa infection through augmenting
Bayes, Hannah K. +2 more
core +1 more source
Intraosseous sarcoidosis imitating peri‐implantitis: A case study
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska +2 more
wiley +1 more source

