Results 121 to 130 of about 1,138,448 (263)

Surgical correction of a double congenital hernia in a veal calf

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This clinical case report describes the rare occurrence and successful surgical management of two simultaneous congenital hernias, umbilical and perineal, in a crossbred veal calf. At 5 days of age, the animal, weighing approximately 40 kg, showed visible swelling in the umbilical and perineal regions together with a congenital tail ...
Andrea Spadaro   +4 more
wiley   +1 more source

Clinical and radiological characteristics of parenchymal and meningeal spinal tuberculosis

open access: yesBMC Infectious Diseases
Background Spinal tuberculosis is a rare condition that can result in significant neurological impairments. It is typically classified into two main types based on the anatomical involvement: parenchymal and meningeal.
Qiu-Lan Shan   +7 more
doaj   +1 more source

Drug-resistant spinal tuberculosis - Current concepts, challenges, and controversies.

open access: yesJournal of Clinical Orthopaedics and Trauma, 2020
The alarming global increase in drug-resistant strains plagues the global fight to end tuberculosis (TB), especially in developing countries. The often reported poor treatment outcomes, sequelae, and lack of best practice guidelines in drug-resistant ...
D. C. R. Soundararajan   +4 more
semanticscholar   +1 more source

FGF21‐Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
FGF21 upregulates SIRT1 to promote the deacetylation of FOXO3 at sites K241, K258, K289, and K568, thereby activating PINK1/Parkin‐dependent mitophagy, suppressing nucleus pulposus cell senescence, and delaying intervertebral disc degeneration. ABSTRACT Intervertebral Disc Degeneration (IDD) is a common degenerative spinal disease and a leading cause ...
Zuo‐long Wu   +7 more
wiley   +1 more source

Analysis of Humira, Electro-Acupuncture, and Pulsatile Dry Cupping on Reducing Joint Inflammation in Patients with Rheumatoid Arthritis [PDF]

open access: yes, 2015
Humira, an anti-TNF drug aimed at decreasing inflammation in Rheumatoid Arthritis patients, can cause skin diseases from rashes to skin cancer. Humira works by blocking the chemical receptor RANKL which inhibits the production of osteoclasts. Osteoclasts
Noll, Natalie
core   +1 more source

Spinal tuberculosis: diagnosis and management. [PDF]

open access: yes, 2011
The spinal column is involved in less than 1% of all cases of tuberculosis (TB). Spinal TB is a very dangerous type of skeletal TB as it can be associated with neurologic deficit due to compression of adjacent neural structures and significant spinal ...
Karimi Yarandi, Kourosh   +5 more
core   +3 more sources

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

open access: yesImmunology, Volume 177, Issue 4, Page 784-797, April 2026.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si   +4 more
wiley   +1 more source

Durvalumab combined with concurrent chemoradiotherapy in patients with limited‐stage small cell lung cancer: A prospective, single‐arm, phase 2 clinical trial

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
Abstract Background The current standard treatment for limited‐stage small cell lung cancer (LS‐SCLC) is concurrent chemoradiotherapy (cCRT) plus consolidation immunotherapy, with or without prophylactic cranial irradiation (PCI). However, it remains unknown whether administering immunotherapy concurrently with chemoradiotherapy confers additional ...
Chunyang Song   +11 more
wiley   +1 more source

Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis [PDF]

open access: yes, 2014
© 2014 Sridhar et al.; licensee BioMed Central Ltd.Background: Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and ...
Chan, JFW, Sridhar, S, Yuen, KY
core   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen   +12 more
wiley   +1 more source

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