Results 31 to 40 of about 40,707 (171)

Synthetic vertebral body implantation Functional outcome in management of spinal disorders

مجلة كلية الطب, 2016
Background: Synthetic vertebral body replacement has been widely used recently to treat different spinal conditions affecting the anterior column. They arrange from trauma, infections and even tumor conditions Objective: To assess the functional outcome ...
Moneer K. Faraj
doaj   +1 more source

Mycobacterium Tuberculosis in Spinal Tuberculosis.

Asian spine journal, 2017
Even in an era of remarkable medical advances, there is an issue of why tuberculosis remains in the list of disastrous diseases, afflicting humans and causing suffering. There has not been a plausible answer to this, and it has been suggested that clinicians and medical scientists could presently not win the war against the tubercle bacilli.
Moon, Myung-Sang, Kim, Sung-Sim, Moon, Han-Lim, Kim, Dong-Hyeon   +3 more
openaire   +2 more sources

Infliximab-related tubercular spinal epidural abscess without osseous involvement in a patient with Crohn’s disease: A case report

Indian Spine Journal, 2021
Tubercular spinal epidural abscess without osseous involvement is an extremely rare presentation of spinal tuberculosis. We report a case of perianal Crohn’s disease, who developed a tubercular epidural abscess in lumbosacral spine without osseous ...
Phani Kiran Surapuraju, Srinivas M., Subramanian Swaminathan   +2 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis

Journal of Orthopaedic Surgery and Research
Background Spinal Tuberculosis (STB) constitutes a common form of tuberculosis and is more widespread in developing countries. Not only is it one of the principal causes of spinal deformity but also it may trigger severe neurological impairments, thereby
Lijun Feng, Mengqi Zhu, Xu Zhang, Ningkui Niu, Zhiyun Shi   +4 more
doaj   +1 more source

Early diagnosis of spinal tuberculosis by magnetic resonance: perfusion weighted imaging in a rabbit model

BMC Medical Imaging, 2022
Highlights 1. A rabbit spinal tuberculosis model was established. 2. Various parameters in the early MR-PWI analysis were different in two groups. 3. MR-PWI may provide valuable imaging evidence for diagnosis and treatment of spinal tuberculosis.
Xiaochen Liu, Yunlin Wang, Wenxiao Jia
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

The rabbit model for spinal tuberculosis: An overview

Journal of Orthopaedic Surgery
Mycobacterium tuberculosis infection has emerged as a global public health issue, predominantly manifesting as pulmonary tuberculosis. Bone and joint tuberculosis, with spinal tuberculosis accounting for approximately 50%, represents a significant form ...
Jingwen Jia, Mingtao Zhang, Zhenyu Cao, Xuchang Hu, Shuanhu Lei, Yizhi Zhang, Xuewen Kang   +6 more
doaj   +1 more source

Biportal Endoscopic Posterior Open‐Window Focal Debridement and Lavage for Sacroiliac Joint Tuberculosis

Arthroscopy Techniques, EarlyView.
Abstract Sacroiliac joint tuberculosis (SJT), although relatively uncommon, may lead to severe destruction and functional impairment of the sacroiliac joint. Surgical intervention is recommended for patients with significant joint destruction, mild cystic changes, or sacroiliac joint instability. Early bone fusion may be facilitated through drainage of
Wei Cheng, Wei Zhang, Hao Pan, Gaoyong Jia   +3 more
wiley   +1 more source