Results 101 to 110 of about 1,339,212 (357)

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

MicroRNAs as fibrosis markers in patients with hypersensitivity pneumonitis

Медицинская иммунология
Hypersensitivity pneumonitis (HP) is a complex interstitial pulmonary syndrome. This clinical entity is characterized by sensitization to a specific antigen.
G. S. Shepelkova, A. S. Zaytseva, V. V. Evstifeev, E. N. Adamovskaya, E. I. Shmelev, V. V. Yeremeev   +5 more
doaj   +1 more source

Infection control and tuberculosis among health care workers in Viet Nam, 2009-2013: a cross-sectional survey

BMC Infectious Diseases, 2016
Background Data on tuberculosis (TB) among health care workers (HCW) and TB infection control (TBIC) indicators are rarely available at national level. We assessed multi-year trends in notification data of TB among HCW and explored possible associations ...
Edine W. Tiemersma, Nguyen Thien Huong, Pham Hoang Yen, Bui Thi Tinh, Tran Thi Bich Thuy, Nguyen Van Hung, Nguyen Thanh Mai, Suzanne Verver, Agnes Gebhard, Nguyen Viet Nhung   +9 more
doaj   +1 more source

Antimicrobial effects of folk medicinal plants from the North of Iran against Mycobacterium tuberculosis [PDF]

, 2015
Background: Medicinal plants have been used traditionally in Golestan province (north of Iran), against Mycobacterium tuberculosis or the clinical signs of tuberculosis (TB).
Davoodi, H., Ghaemi, E.A., Ghazisaidi, K., Jahanpour, N., Jahanpour, S., Mazandarani, M., Samet, M.   +6 more
core  

Enhancing Spinal Metastasis Detection and Feature Evaluation on Computed Tomography Scans Using Deep‐Learning Systems

Advanced Intelligent Systems, EarlyView.
A deep‐learning system (DLS) is developed for the automatic detection of spinal metastases and the evaluation of associated features using computed tomography imaging. A multireader, multicase analysis and a prospective multicenter cohort study are conducted to evaluate the diagnostic performance.
Zhiyu Wang, Guangyu Yao, Shengyuan Xu, Yifeng Gu, Yujie Chang, Jing Sun, Jingyi Guo, Shiqi Peng, Bolin Lai, Xiaoyun Zhang, Chunbin Wang, Haiying Jiang, Surong Chen, Yanfeng Wang, Ya Zhang, Yuehua Li, Hui Zhao   +16 more
wiley   +1 more source

Correlations between expression levels of genes encoding multifunctional YB-1 protein, inflammatory cytokines and multidrug resistance P-gp protein in surgical material from patients with lung tuberculosis

Медицинская иммунология
YB-1 is a multifunctional protein, being a transcription factor involved in the regulation of numerous cellular processes. YB-1 is an important factor in molecular cascades that regulate the response to the pathogen invasion, inflammatory activity, as ...
M. V. Erokhina, E. N. Pavlova, E. A. Scherbakova, E. Yu. Rybalkina, L. N. Lepekha, R. V. Tarasov, E. K. Tarasova   +6 more
doaj   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

Animal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu, Selase Ativui, Michael Ofori, George Owusu, Cynthia Amaning Danquah, Paul Poku Sampene Ossei   +5 more
wiley   +1 more source

Exploring prospects of novel drugs for tuberculosis [PDF]

, 2012
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However, even for the treatment of drug-sensitive tuberculosis,
Grobusch, M. P., Janssen, S., Jayachandran, R., Khathi, L., Pieters, J., Zinsstag, J.   +5 more
core   +1 more source

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

Annals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal, Sabine E. Olie, Michel van Weeghel, Bauke V. Schomakers, Frédéric M. Vaz, I‐PACE Study Group, Diederik van de Beek, Matthijs C. Brouwer   +7 more
wiley   +1 more source

GROWTH OF MYCOBACTERIUM TUBERCULOSIS VAR. HOMINIS IN AGITATED CULTURE [PDF]

, 1952
Frederick C. Kull, Madelon R. Grimm
openalex   +1 more source