Tuberculous meningitis is possibly complicated with multiple cerebral infarctions and basal meningitis, and the mortality and neurological prognosis is reportedly poor.
Shinnosuke Fukushima+4 more
doaj +3 more sources
Treatment of Tuberculous Meningitis [PDF]
The incidence of tuberculous meningitis is at last rapidly diminishing in this country, yet in 1958 there were still 369 newly notified cases in England and Wales (Ministry of Health, 1959). As the untreated disease is inevitably fatal, this incidence is still an important therapeutic challenge.
J. G. Kerr
+10 more sources
Tuberculous meningitis (TBM) is caused by Mycobacterium tuberculosis and kills or disables around a half of sufferers. It is commonest in young children and those infected with HIV, but can affect all age-groups. TBM presents with non-specific symptoms over days or weeks, followed by worsening headaches, fever, and vomiting.
Van, T, Farrar, J
+7 more sources
Outcomes of tuberculous meningitis in children: a case review study
Background Tuberculous meningitis is a severe extrapulmonary complication of tuberculosis, with high morbidity and mortality rates. Objective To assess the relationship between presenting clinical characteristics and outcomes of pediatric tuberculous ...
Yazid Dimyati+4 more
doaj +1 more source
Standardized methods for enhanced quality and comparability of tuberculous meningitis studies [PDF]
Tuberculous meningitis remains a major cause of death and disability in tuberculosis endemic areas, especially in young children and immunocompromised adults.
Aarnoutse, R+18 more
core +5 more sources
Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study. [PDF]
BACKGROUND: WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50-70% and culture sensitivity of about 60%.
ASTRO-CM Trial Team+12 more
core +1 more source
Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla+12 more
core +4 more sources
Quantitative proteomics for identifying biomarkers for tuberculous meningitis
Introduction Tuberculous meningitis is a frequent extrapulmonary disease caused by Mycobacterium tuberculosis and is associated with high mortality rates and severe neurological sequelae.
Kumar Ghantasala S Sameer+16 more
doaj +1 more source
Molecular epidemiology of tuberculous meningitis isolates from Thailand: a collective summary
Background Tuberculosis infection of meninges or tuberculous meningitis is an important serious form of Mycobacerium tuberculosis infection. This nervous system infection can lead to complex clinical problem.
Beuy Joob, Viroj Wiwanitkit
doaj +1 more source
Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]
Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla+8 more
core +1 more source