Results 11 to 20 of about 178,050 (257)
Clinical Case Reports, 2023 Tuberculous meningitis is possibly complicated with multiple cerebral infarctions and basal meningitis, and the mortality and neurological prognosis is reportedly poor.
Shinnosuke Fukushima +4 more
doaj +4 more sources
Tuberculous Meningitis in Children: Reducing the Burden of Death and Disability
Pathogens, 2021 Tuberculous meningitis disproportionately affects young children. As the most devastating form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity even if treated.
Julie Huynh +5 more
doaj +2 more sources
Treatment of Tuberculous Meningitis [PDF]
The Lancet, 1953 The incidence of tuberculous meningitis is at last rapidly diminishing in this country, yet in 1958 there were still 369 newly notified cases in England and Wales (Ministry of Health, 1959). As the untreated disease is inevitably fatal, this incidence is still an important therapeutic challenge.
J. G. Kerr
openalex +6 more sources
The pathogenesis of tuberculous meningitis [PDF]
Journal of Leukocyte Biology, 2019 Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM), which represents a medical emergency associated with high rates of mortality
A. Davis +4 more
semanticscholar +4 more sources
Medicine, 2013 Tuberculous meningitis (TBM) is caused by Mycobacterium tuberculosis and kills or disables around a half of sufferers. It is commonest in young children and those infected with HIV, but can affect all age-groups. TBM presents with non-specific symptoms over days or weeks, followed by worsening headaches, fever, and vomiting.
Van, T, Farrar, J
+7 more sources
Adjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults
New England Journal of Medicine, 2023 Background Adjunctive corticosteroids are widely used to treat HIV-associated tuberculous meningitis despite limited data supporting their safety and efficacy. Methods We conducted a randomized double-blind placebo-controlled trial in HIV-positive adults
Joseph Donovan +29 more
semanticscholar +1 more source
Microbiology spectrum, 2022 As the most severe form of tuberculosis, the pathogenesis of tuberculous meningitis (TBM) is still unclear. Gut microbiota dysbiosis plays an important role in a variety of central nervous system diseases.
Shanshan Li +11 more
semanticscholar +1 more source
Journal of Clinical Investigation, 2022 Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB), requiring 12 months of multidrug treatment for cure, and is associated with high morbidity and mortality.
Camilo A. Ruiz-Bedoya +15 more
semanticscholar +1 more source
Improving Technology to Diagnose Tuberculous Meningitis: Are We There Yet?
Frontiers in Neurology, 2022 Diagnosis of tuberculous meningitis (TBM) remains challenging due to a paucity of high-performance diagnostics. Even those that have reasonable sensitivity are not adequate to ‘rule out' TBM.
K. Ssebambulidde +4 more
semanticscholar +1 more source
The global burden of tuberculous meningitis in adults: A modelling study
PLOS Global Public Health, 2021 Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. The incidence and mortality of TBM is unknown due to diagnostic challenges and limited disaggregated reporting of treated TBM by existing surveillance systems. We aimed to estimate the
P. Dodd +9 more
semanticscholar +1 more source