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Tuberculous meningitis in infancy
Pediatric Neurology, 2002The lack of specific symptoms and signs in patients with tuberculous meningitis makes early diagnosis difficult. To our knowledge, there has been no report in the literature focusing on tuberculous meningitis patients younger than 1 year of age. In this report, we reviewed the clinical features and laboratory findings of seven infants with tuberculous ...
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Tuberculous meningitis in children
Current Treatment Options in Neurology, 2002Initial empiric treatment for central nervous system (CNS) tuberculosis should include four antituberculous drugs until results of cultures and sensitivities are available. Treatment should include isoniazid, rifampin, pyrazinamide, and either ethambutol or streptomycin. Total treatment should extend for 12 months.
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Tuberculous meningitis in children
Indian Journal of Pediatrics, 19561. A survey of 65 cases occurring from 1944 to 1954 has been presented. 2. The value of the anti-tuberculous drugs in treatment has been discussed 3. The importance of early diagnosis and institution of early treatment have been emphasized. 4.
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Tuberculous meningitis: The challenges
Neurology India, 2010Tuberculous meningitis (TBM) is a serious meningitic infection commonly found to occur in the developing countries endemic to tuberculosis. Based on the clinical features alone, the diagnosis of TBM can neither be made nor excluded with certainty. Unfortunately there is still no single diagnostic method that is both sufficiently rapid and sensitive ...
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The treatment of tuberculous meningitis
Tubercle, 1950Any review of the treatment of tuberculous meningitis by streptomycin at this stage must be depressing. Human memory is so short that we forget the inevitable and speedy deaths of the years before 1947 and concentrate on the disappointing failures of treatment with streptomycin after 8 or 10 or 14 months of apparent response. It is far too early yet to
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Chemotherapy for Tuberculous Meningitis
New England Journal of Medicine, 2016Tuberculous meningitis, the most destructive form of tuberculosis, continues to be associated with considerable mortality and morbidity; among children, it is the major cause of death resulting from tuberculosis. The consequences of tuberculous meningitis are yet again clearly shown in the article by Heemskerk et al. in this issue of the Journal.1 This
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TUBERCULOUS MENINGITIS IN CHILDHOOD
Medical Journal of Australia, 1975The 43 cases of tuberculous meningitis treated at the Royal Children's Hospital, Melbourne, over the 15-year period from January, 1954, to December, 1969, are reviewed in detail. With "triple drug" antituberculosis therapy, 19 patients made a full recovery and seven died. Of the other 17, 11 had major permanent sequelae.
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Tuberculous Meningitis in Adults
Southern Medical Journal, 1967This review illustrates that tuberculous meningitis, characteristic of recent infection, has moved from childhood to adult life. This would be anticipated to accompany the demonstrated later acquisition of tuberculosis of today.
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Ethambutol in Tuberculous Meningitis
Chest, 1972Ethambutol (EMB) was present in appreciable concentrations in the cerebrospinal fluid of patients with tuberculous meningitis and after a dose of 25 mg/kg, in a majority of cases, the cerebrospinal fluid concentration was 1 μg/ml or higher. Combination chemotherapy including EMB was effective in the treatment of six of eight patients with tuberculous ...
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Tuberculous meningitis in children
The Indian Journal of Pediatrics, 1977Of the 280 cases of tuberculous meningitis, 75.8 per cent were under 5 years of age. The males were twice as often affected as females. Testing for neck stiffness in a young febrile child is important for early diagnosis of tuberculous meningitis. Tuberculin test was negative in 18 per cent of cases.
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