Results 141 to 150 of about 347,356 (359)

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

The risk of epilepsy after neonatal seizures

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16288 Abstract Aim To estimate the cumulative risk of epilepsy after neonatal seizures and identify subpopulations at increased risk. Method This was a nationwide register‐based cohort study including all children born in Denmark between 1997 and 2018.
Jeanette Tinggaard, Signe V. Pedersen, Mads L. Larsen, Andreas K. Jensen, Gorm Greisen, Bo M. Hansen, Christina E. Hoei‐Hansen   +6 more
wiley   +1 more source

Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder. [PDF]

, 2017
Autism spectrum disorder (ASD) is a behaviorally defined disorder affecting 1 in 68 children. Currently, there is no known cause for the majority of ASD cases nor are there physiological diagnostic tools or biomarkers to aid behavioral diagnosis.
Ashwood, Paul, Onore, Charity, Van de Water, Judy, Yang, Houa   +3 more
core   +1 more source

Long-Term Use of Everolimus in Patients with Tuberous Sclerosis Complex: Final Results from the EXIST-1 Study

PLoS ONE, 2016
Background Everolimus, a mammalian target of rapamycin (mTOR) inhibitor, has demonstrated efficacy in treating subependymal giant cell astrocytomas (SEGAs) and other manifestations of tuberous sclerosis complex (TSC).
D. N. Franz, E. Belousova, S. Sparagana, E. Bebin, M. Frost, R. Kuperman, O. Witt, Michael H. Kohrman, J. Flamini, Joyce Y. Wu, P. Curatolo, P. D. de Vries, N. Berkowitz, J. Niolat, S. Jóźwiak   +14 more
semanticscholar   +1 more source

Unusual Size of Intraventricular Spongioblastoma in a Case of Tuberous Sclerosis [PDF]

, 1935
Lauren C. Cook, Alexa Meyer
openalex   +1 more source

Deep developmental phenotyping in children with tuberous sclerosis complex, with and without autism

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16312 Abstract Aim To characterize autism and co‐occurring tuberous sclerosis‐associated neuropsychiatric disorders (TAND) in children with tuberous sclerosis complex (TSC), addressing evidence gaps by using deep developmental phenotyping in a single cohort.
Rebecca A. Mitchell, Francesca Lami, Sarah M. Barton, A. Simon Harvey, Katrina Williams   +4 more
wiley   +1 more source

Cardiovascular considerations in tuberous sclerosis

Pediatria i Medycyna Rodzinna, 2017
Tuberous sclerosis complex is a genetic condition with an autosomal dominant pattern of inheritance, with an incidence of approximately 1:10,000, and 1:6,800 in the paediatric population, caused by a mutation of either of two genes: TSC1 on chromosome ...
Joanna Kohut, Bogusław Mazurek, Jacek Pająk, Lesław Szydłowski, Aleksandra Morka   +4 more
doaj   +1 more source

The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. [PDF]

, 2006
Causes and contributing factors for autism are poorly understood. Evidence suggests that prevalence is rising, but the extent to which diagnostic changes and improvements in ascertainment contribute to this increase is unclear.
Croen, Lisa A, Hansen, Robin, Hertz-Picciotto, Irva, Jones, Carrie R, Pessah, Isaac N, van de Water, Judy   +5 more
core   +1 more source

Clinical Characteristics of Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis Complex. [PDF]

, 2019
Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA).
Agranovich, Oleg, Altunbasak, Sakir, Anlar, Banu, Belousova, Elena, Belyaev, Oleg Valeryevich, Benedik, Mirjana P., Carter, Tom, Cottin, Vincent, Curatolo, Paolo, D'Amato, Lisa, D'Augères, Guillaume Beaure, Dahlin, Maria, De Vries, Petrus J., Endo, Shoichi, Ferreira, José C., Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Horie, Shigeo, Imai, Katsumi, Inoue, Yoshikazu, Jansen, Anna C., Jozwiak, Sergiusz, Kaneda, Mari, Kaneko, Hideo, Kingswood, John C., Kirino, Tomoko, Kubota, Masaya, Lawson, John A., Levitina, Elena Vladislavovna, Lvova, Olga, Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O'Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Sauter, Matthias, Serdaroglu, Ayse, Shah, Seema, Shinohara, Nobuo, Takahashi, Yukitoshi, Tohyama, Jun, TOSCA Consortium and TOSCA Investigators, Touraine, Renaud, Uchida, Yasushi, Uruno, Katsuhisa, Yapici, Zuhal, Youroukos, Sotiris, Zonnenberg, Bernard   +49 more
core   +2 more sources

Case of tuberous sclerosis and haemorrhagic retinophathy (with fundus photographs) [PDF]

, 1967
A. M. Dyer, Robert Hill, R. M. Rowan, William Taylor   +3 more
openalex   +1 more source