Results 221 to 230 of about 71,608 (348)

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

open access: yesMedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang   +10 more
wiley   +1 more source

A 24-year-Old woman with recurrent pneumothoraces

open access: yesRespiratory Medicine Case Reports
Lymphangioleiomyomatosis (LAM) is an abnormal proliferation of smooth muscle-like cells and may occur sporadically or in association with tuberous sclerosis complex.
Daniel J. Greenberg   +3 more
doaj  

Blood Biomarkers to Identify Renal Angiomyolipomas in People With Tuberous Sclerosis Complex. [PDF]

open access: yesNeurol Genet
Balthazard R   +12 more
europepmc   +1 more source

Analysis of 65 tuberous sclerosis complex (TSC) patients byTSC2DGGE,TSC1/TSC2MLPA, andTSC1long-range PCR sequencing, and report of 28 novel mutations

open access: gold, 2005
Nanna Dahl Rendtorff   +7 more
openalex   +1 more source

Massive hepatic angiomyolipoma in a young woman with tuberous sclerosis complex: Significant clinical improvement during tamoxifen treatment [PDF]

open access: hybrid, 2008
Ilaria Lenci   +7 more
openalex   +1 more source

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1004-1025, August 2025.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes   +6 more
wiley   +1 more source

Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: genotype – phenotype correlations and comparison of diagnostic DNA techniques in Tuberous Sclerosis Complex

open access: bronze, 2005
Őzgür Sancak   +9 more
openalex   +1 more source

Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis [PDF]

open access: bronze, 2008
John J. Bissler   +11 more
openalex   +1 more source

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