Results 71 to 80 of about 5,403,298 (185)

Risk of Antiepileptic Drug Withdrawal in Tuebrous Sclerosis

Pediatric Neurology Briefs, 2003
Of 122 children with tuberous sclerosis complex (TSC) followed at Texas Scottish Rite Hospital for Children, Dallas, TX, 106 (86.9%) had a history of epilepsy.
J Gordon Millichap
doaj   +1 more source

Complete lesion resection and early surgical intervention are favorable factors for long‐term seizure freedom in drug‐resistant epileptic spasms

Epilepsia Open, EarlyView.
Abstract Objective Epileptic spasms (ES) in children carry a high risk of neurodevelopmental delay, yet predictors of long‐term surgical outcome remain incompletely defined. This study aimed to evaluate seizure outcomes following epilepsy surgery and to identify independent prognostic factors for postoperative recurrence.
Hua Li, Yao Wang, Qiang Guo, Junxi Chen, Kaihui Li, Danfang Li, Qinghua Tan, Jing Guo   +7 more
wiley   +1 more source

Tuberous Sclerosis Complex

, 2017
Tuberous sclerosis complex (TSC) is a disease, commonly classified as a neurocutaneous disorder, which may result in benign tumors throughout the brain and body, skin lesions, epilepsy, and cognitive/behavioral difficulties.
Tanjala T. Gipson, Andrea Poretti, Michael V. Johnston, Rebecca McClellan   +3 more
core   +1 more source

Clinical characteristics of subependymal giant cell astrocytoma in tuberous sclerosis complex [PDF]

, 2019
SEGA; TOSCA; Tuberous sclerosis complexSEGA; TOSCA; Complejo de esclerosis tuberosaSEGA; TOSCA; Complex d'esclerosi tuberosaBackground: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous ...
Perkovic Benedik, Mirjana, Curatolo, Paolo, Jansen, Anna C., Cottin, Vincent, Macaya Ruíz, Alfons, Carter, Tom, Belousova, Elena   +6 more
core   +1 more source

mTOR Inhibition and Tuberous Sclerosis Prevention

Pediatric Neurology Briefs, 2013
Investigators at Children's Memorial Health Institute, Warsaw, Poland, report monozygotic twin sisters with tuberous sclerosis complex (TSC), one treated with the mTOR inhibitor everolimus since age 4 years.
J Gordon Millichap
doaj   +1 more source

Quality of life in patients with Tuberous Sclerosis Complex (TSC) [PDF]

, 2019
BACKGROUND: The quality of life (QoL) of patients with Tuberous Sclerosis Complex (TSC) has not been studied before. We aimed to investigate the impact of the disease on QoL. We studied the QoL of 91 TSC patients who have attended the Bath TSC clinic, UK
Mallick, AA, Amin, S, O'Callaghan, Finbar, O'Callaghan, F, Amin, Sam, Lux, A, Mallick, Andrew A, Lux, Andrew   +7 more
core   +2 more sources

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatment was created and sent to 45 member institutions of the Pediatric ...
Akshat Katyayan, Christina Briscoe, Sonam Bhalla, Sonal Bhatia, Gozde Erdemir, Chellamani Harini, Senyene E. Hunter, John R. Mytinger, Duyu Nie, Archana Pasupuleti, Shital H. Patel, Debopam Samanta, Amanda Sandoval Karamian, Avantika Singh, Deepa Sirsi, Danielle S. Takacs, Shaun A. Hussain   +16 more
wiley   +1 more source

Long-term cognitive outcomes in tuberous sclerosis complex [PDF]

, 2020
Aim: To investigate the interdependence between risk factors associated with long-term intellectual development in individuals with tuberous sclerosis complex (TSC).
Carcani-Rathwell, I, Steenbruggen, J, Sampson, JR, Lydon, A, Barker, ED, Griffiths, PD, Patrick F Bolton, Tuberous Sclerosis 2000 Study Group, Grp, TSS, Fryer, AE, Hunt, A, Liang, H, Clifford, M, Underwood, L, Elmslie, FV, O'Callaghan, FJK, Granader, Y, Falconer, C, Mcewen, FS, Cook, JA, Miedzybrodzka, ZH, Kingswood, JC, Sheerin, F, Charlotte Tye, Connolly, C, Fiona S Mcewen, Baines, D, Sheehan-Dare, R, Tye, C, Philip, SG, Saggar, AK, Attard, V, Clarke, A, Bolton, PF, Higgins, N, Lisa Underwood, Holan Liang, Brayne, C, Srivastava, C, Fintan Sheerin, Davies, DM, Crawford, H, Rogers, H, Kerr, BA, Morrison, PJ, Seri, S, Oluwo, F, John R W Yates, Woodhouse, E, Yates, JRW, Lam, WWK, Shepherd, CH, Edward D Barker, Emma Woodhouse, Haslop, M   +54 more
core   +1 more source

Neuropsychological profile in tuberous sclerosis complex: a study of clinical and cognitive variables in a cohort from Brazil

Arquivos de Neuro-Psiquiatria
Background Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a wide clinical, cognitive, and behavioral expressivity.
Laís Faria Masulk Cardozo, Mariana Richartz Schwind, Ana Paula Almeida de Pereira, Luiz Gustavo Dufner-Almeida, Luciana Amaral Haddad, Isac Bruck, Sérgio Antonio Antoniuk   +6 more
doaj   +1 more source

Visual Processing in Infants with Tuberous Sclerosis Complex

Pediatric Neurology Briefs, 2016
Investigators from Harvard University and UCLA have reported that despite evidence of structural abnormalities in the visual pathway of animal models and children with tuberous sclerosis complex (TSC), visual evoked potentials (VEPs) in 12-month old ...
Tracy S. Gertler, Srishti Nangia
doaj   +1 more source