Results 141 to 150 of about 3,273 (253)

The HAMMER: High altitude multiple mission environmental researcher [PDF]

open access: yes
At the equator, the ozone layer ranges from 65,000 to 130,000+ feet which is beyond the capabilities of the ER-2, NASA's current high altitude reconnaissance aircraft.
Amaro, Ernesto   +6 more
core   +1 more source

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

open access: yesArtificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly   +11 more
wiley   +1 more source

A limpet's eye view of post‐glacial isostasy: fixed biological indicators provide new sea‐level index points for the Mid‐Holocene relative highstand in eastern Northern Ireland

open access: yesBoreas, EarlyView.
Bioerosional scars made by limpets (Patella) on a cliff in Co. Antrim, Northern Ireland, indicate a Mid‐Holocene RSL of +7.8±0.55 m relative to local mid‐tide level today. This is higher than previous empirical data for the region and extrapolated levels from raised shorelines in Scotland but consistent with some recent GIA models.
Michael J. Simms, Paula J. Reimer
wiley   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu   +4 more
wiley   +1 more source

Alloy chemistry and microstructural control to meet the demands of the automotive Stirling engine [PDF]

open access: yes
The automotive Stirling engine now under development by DOE/NASA as an alternative to the internal combustion engine, imposes severe materials requirements for the hot portion of the engine.
Stephens, J. R.
core   +1 more source

An Easy Method to Sample Headspace Pheromones in the Field

open access: yesEthology, EarlyView.
Females of the orb‐web spider Argiope bruennichi produces a pheromone to attract males for mating. Most of our knowledge about the pheromone and its strategical use by the females is known from the laboratory. While we have confidence in the validity of these results, we wanted to make sure and measure pheromones in the field.
Zoe Dössel   +2 more
wiley   +1 more source

Development of supercritical pressure cryogenic storage and supply systems incorporating the radial bumper-discrete shield design Final report [PDF]

open access: yes
Design of super critical pressure cryogenic storage and supply equipment with radial bumper ...
Gerth, B., Lundeen, R.
core   +1 more source

Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition

open access: yesThe FEBS Journal, EarlyView.
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis   +9 more
wiley   +1 more source

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