Results 181 to 190 of about 59,556 (258)

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez   +8 more
wiley   +1 more source

Narrative review of strategies for blood product shelf‐life extension

open access: yes
Transfusion, EarlyView.
Mike Akaraphanth   +7 more
wiley   +1 more source

Development of Artificial Sebaceous Gland‐Integrated In Vitro Human Skin Model

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 6, 16 March 2026.
Uniform 3D artificial sebaceous gland spheroids, termed SebaSpheres, are generated at high throughput using a microfluidic platform and structurally integrated into a collagen‐based skin construct containing fibroblasts and keratinocytes. This work presents a modular and scalable fabrication and integration strategy for incorporating sebaceous gland ...
Daeun Ryu   +7 more
wiley   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang   +9 more
wiley   +1 more source

The basic anaesthesia machine. [PDF]

open access: yesIndian J Anaesth, 2013
Gurudatt C.
europepmc   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

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