Results 171 to 180 of about 1,812 (217)

Transcriptomic atlas reveals organ-specific disease tolerance in sickle cell mice. [PDF]

open access: yesBlood Adv
Grunenwald A   +9 more
europepmc   +1 more source

Cell Catcher: A New Method to Extract and Preserve Live Renal Cells from Urine. [PDF]

open access: yesKidney360
Nazmutdinova K   +7 more
europepmc   +1 more source

Potassium-related inherited tubulopathies

Cellular and Molecular Life Sciences, 2006
Hyper- and hypokalemia may carry severe clinical consequences. Different regulatory mechanisms, including the kidney, exert a tight regulation of plasma potassium levels. The renal pathway of potassium handling begins in the proximal tubule followed by the fine-tuning of its secretion or absorption at the distal tubule, including the thick ascending ...
Daniel Landau
exaly   +3 more sources

Mitochondrial Dysfunction in Kidney Tubulopathies [PDF]

open access: yesAnnual Review of Physiology
Mitochondria play a key role in kidney physiology and pathology. They produce ATP to fuel energy-demanding water and solute reabsorption processes along the nephron. Moreover, mitochondria contribute to cellular health by the regulation of autophagy, (oxidative) stress responses, and apoptosis.
Jeroen H F De Baaij
exaly   +3 more sources

Inherited Renal Tubulopathies—Challenges and Controversies [PDF]

open access: yesGenes, 2020
Electrolyte homeostasis is maintained by the kidney through a complex transport function mostly performed by specialized proteins distributed along the renal tubules. Pathogenic variants in the genes encoding these proteins impair this function and have consequences on the whole organism.
Daniela S Iancu
exaly   +3 more sources

Diabetic Tubulopathy: An Emerging Entity

2011
In chronic glomerulopathic disease, renal function correlates more with the degree oftubulointerstitial injury than that of the glomerular lesions. Proteinuria may be one of the pathologic links between these two intrarenal compartments. It is apparent that the proximal tubular epithelial cell (PTEC) assumes a proinflammatory and profibrotic role ...
Lai, KN, Tang, SCW, Leung, JCK
openaire   +4 more sources

Proteomics and tubulopathies.

Journal of nephrology, 2010
In the last thirty decade, with the emergence of new trends in molecular biology and advances in high-throughput technologies, much progress has been made in basic renal physiology. Molecular genetics has allowed the identification and elucidation of the structure, function and effects of the mutations of several of the main transporters and ion ...
VILASI A, CAPASSO, Giovambattista
openaire   +2 more sources

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