Waldenström Macroglobulinemia: Unusual Presentation With Cast Nephropathy/Light Chain Tubulopathy
Clinical Medicine Insights: Case Reports, 2019 Cast Nephropathy/Light chain tubulopathy is usually present in patients with multiple myeloma and is very rare in patients with Waldenstrom Macroglobulinemia. There are very few case reports mentioned in the literature.
Prerna Rastogi, Muddasir Ashraf
exaly +3 more sources
Screening for an Underlying Tubulopathy in Children With Growth Failure, Simply Maths?
Frontiers in Pediatrics, 2022 BackgroundInvolving pediatric nephrological input in the clinical diagnostic work-up of children with short stature, gave rise to the hypothesis that the presence of an underlying renal tubular disorder in children with short stature is possibly ...
Kristien J Ledeganck +2 more
exaly +4 more sources
Tubular dysfunction in stable adult sickle cell patients in Kinshasa: prevalence and associated factors - a cross-sectional study [PDF]
Renal FailureRenal complications of sickle cell disease (SCD) often begin with tubular dysfunction (TD), yet this entity remains insufficiently recognized in African populations. Data from adults in Kinshasa are particularly scarce.
Yannick Mompango Engole +10 more
doaj +2 more sources
Noncrystalline light-chain proximal tubulopathy: a retrospective study from a single institute of China [PDF]
Renal FailureLight-chain proximal tubulopathy (LCPT) is a rare disease, which is classified as crystalline or noncrystalline based on the cytoplasmic inclusions in the proximal tubules. This study aimed to investigate the clinical features of noncrystalline LCPT from
Jie-qiong Yao +7 more
doaj +2 more sources
Kidney Medicine, 2019 Light chain proximal tubulopathy is a rare M-proteinemia–related nephropathy. The inclusions, composed of light chains in light chain proximal tubulopathy, are generally crystalline, and most exhibit a rhombic shape.
Hiroshi Kataoka +2 more
exaly +3 more sources
Hypokalemic distal tubulopathy secondary to PLA2R-positive membranous nephropathy: an exceptional case [PDF]
Glomerular DiseasesIntroduction: Primary membranous nephropathy, one of the most common primary nephrotic syndromes in adults, rarely has tubular involvement.
Thanawat Vongchaiudomchoke +2 more
doaj +2 more sources
Hydroxychloroquine-induced renal phospholipidosis manifesting as proximal tubulopathy in systemic lupus erythematosus [PDF]
BMC NephrologyBackground Hydroxychloroquine (HCQ)-induced renal phospholipidosis typically manifests as glomerular “zebra bodies”, “myeloid bodies”, and “curvilinear bodies” and is generally considered a benign histological mimic of Fabry disease.
Shun Manabe +12 more
doaj +2 more sources
Biclonal gammopathy with coexistent proximal tubulopathy and cast nephropathy in multiple myeloma: a rare case report [PDF]
BMC NephrologyBackground Multiple myeloma is a hematological malignancy originating from neoplastic plasma cells, typically characterized by the presence of a monoclonal immunoglobulin.
Shanshen Yu, Jia Sun, Xufeng Mei
doaj +2 more sources
Cathepsin resistance mediated by key amino acid substitutions drives intracellular crystallization in light chain proximal tubulopathy [PDF]
Communications BiologyMonoclonal free light chains drive diverse renal pathologies in plasma cell dyscrasias. However, the mechanism of light chain proximal tubulopathy remains poorly understood because sequence data are scarce.
Xin Wang +11 more
doaj +2 more sources
Gitelman and Bartter Syndrome in a Patient With Morbid Obesity: A Case Report and Literature Review [PDF]
Clinical Case ReportsWe present a case study of a 34‐year‐old man with morbid obesity and a suspected Bartter–Gitelman spectrum tubulopathy (without genetic confirmation), weighing 135 kg, and with a BMI of 42.5 kg/m2, who was referred to the metabolic and bariatric surgery ...
Solmaz Hasani +4 more
doaj +2 more sources