Results 161 to 170 of about 6,399 (205)
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Journal of Nephrology, 2010
Abstract In the last thirty decade, with the emergence of new trends in molecular biology and advances in high throughput technologies, much progress has been made in basic renal physiology. Molecular genetics has allowed the identification and elucidation of the structure, function and effects of the mutations of sev eral of the main
VILASI A, CAPASSO, Giovambattista
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Abstract In the last thirty decade, with the emergence of new trends in molecular biology and advances in high throughput technologies, much progress has been made in basic renal physiology. Molecular genetics has allowed the identification and elucidation of the structure, function and effects of the mutations of sev eral of the main
VILASI A, CAPASSO, Giovambattista
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Hypouricemia Related to a Hypersecretional Tubulopathy
Nephron, 2008We present 1 patient with hypouricemia and hyperuricosuria. Serum uric acid level ranged between 1.5 and 1.9 mg/dl and uric acid fractional excretion between 20 and 28%. Apart from that the renal function was normal. The pyrazinamide suppression test gave a normal response showing nearly complete suppression of urate excretion.
Dumont, Isabelle, Decaux, Guy
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Diabetic Tubulopathy: An Emerging Entity
2011In chronic glomerulopathic disease, renal function correlates more with the degree oftubulointerstitial injury than that of the glomerular lesions. Proteinuria may be one of the pathologic links between these two intrarenal compartments. It is apparent that the proximal tubular epithelial cell (PTEC) assumes a proinflammatory and profibrotic role ...
Lai, KN, Tang, SCW, Leung, JCK
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Failure to thrive in children with tubulopathies
Pediatric NephrologyFailure to thrive (FTT) is a common clinical concern in pediatric patients with tubulopathies. Defective tubular handling of solutes, electrolytes, and acid-base balance contributes to impaired growth through both renal and systemic mechanisms.
Rivetti G. +4 more
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Potassium-related inherited tubulopathies
Cellular and Molecular Life Sciences, 2006Hyper- and hypokalemia may carry severe clinical consequences. Different regulatory mechanisms, including the kidney, exert a tight regulation of plasma potassium levels. The renal pathway of potassium handling begins in the proximal tubule followed by the fine-tuning of its secretion or absorption at the distal tubule, including the thick ascending ...
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Transient renal tubulopathy in a Labrador retriever
Journal of Small Animal Practice, 2001A four‐month‐old male Labrador retriever was presented for polyuria, polydipsia and persistent euglycaemic glucosuria. On referral, diagnostic tests demonstrated abnormal fractional excretions of electrolytes, increased urinary excretion of selected amino acids, mild renal tubular acidosis and mild proteinuria, indicating renal tubular dysfunction ...
P M, Jamieson, M L, Chandler
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Transient renal tubulopathy in a racing Greyhound
Australian Veterinary Journal, 2006A 2‐year‐old female Greyhound was presented for inappetence and lethargy. On referral, results of diagnostic tests indicated renal glucosuria, increased excretion of selected amino acids and abnormal fractional excretion of electrolytes consistent with renal tubular dysfunction. Systemic blood pressure was elevated.
L A, Abraham, D, Tyrrell, J A, Charles
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Acta medica Austriaca, 1976
1. Defects in transport systems of renal tubules are caused by partial tubular dysfunction without preceeding renal disease. There is a well delineated disturbance for the reabsorption of certain substances. Most commonly the defects in transport of renal tubules are genetically determined. 2.
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1. Defects in transport systems of renal tubules are caused by partial tubular dysfunction without preceeding renal disease. There is a well delineated disturbance for the reabsorption of certain substances. Most commonly the defects in transport of renal tubules are genetically determined. 2.
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Light Chain-Mediated Tubulopathies
2011Immunoglobulin light chains are low molecular weight proteins that are filtered through the glomerulus and reabsorbed into the proximal tubular epithelium by binding initially to a heteromeric receptor complex composed of megalin and cubilin. Saturation of this receptor-mediated endocytotic process results in the presence of free light chains in the ...
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A Physiologic Approach to Hereditary Tubulopathies
20091. The primary function of the proximal tubule is the bulk reabsorption of inorganic and organic solutes.
Marva Moxey-Mims, Paul Goodyer
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