Results 51 to 60 of about 72,617 (249)

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Tudor-SN promotes cardiomyocyte proliferation and neonatal heart regeneration through regulating the phosphorylation of YAP

Cell Communication and Signaling
Background The neonatal mammalian heart exhibits considerable regenerative potential following injury through cardiomyocyte proliferation, whereas mature cardiomyocytes withdraw from the cell cycle and lose regenerative capacities.
Chao Su, Jinzheng Ma, Xuyang Yao, Wei Hao, Shihu Gan, Yixiang Gao, Jinlong He, Yuanyuan Ren, Xingjie Gao, Yi Zhu, Jie Yang, Minxin Wei   +11 more
doaj   +1 more source

Exponential Stability of Higher Order Fractional Neutral Stochastic Differential Equation Via Integral Contractors

Mathematical Methods in the Applied Sciences, Volume 48, Issue 6, Page 6425-6446, April 2025.
ABSTRACT The well‐posedness results for mild solutions to the fractional neutral stochastic differential system with Rosenblatt process with Hurst index Ĥ∈12,1$$ \hat{H}\in \left(\frac{1}{2},1\right) $$ is discussed in this article. To demonstrate the results, the concept of bounded integral contractors is combined with the stochastic result and ...
Dimplekumar N. Chalishajar, Dhanalakshmi Kasinathan, Ramkumar Kasinathan, Ravikumar Kasinathan   +3 more
wiley   +1 more source

Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1

Journal of Biomedical Science
Background Dysregulation of vascular homeostasis can induce cardiovascular diseases and increase global mortality rates. Although lineage tracing studies have confirmed the pivotal role of modulated vascular smooth muscle cells (VSMCs) in the progression
Yichen Wu, Zilong Chen, Zhe Zheng, Xiaoguang Li, Jiangcheng Shu, Ruiqi Mao, Jie An, Siyuan Fan, Ruijie Luo, Yi Guo, Wenjing Xu, Minglu Liang, Kai Huang, Cheng Wang   +13 more
doaj   +1 more source

Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR

Nature Communications, 2018
Tudor interacting repair regulator (TIRR) is a negative regulator of 53BP1 in DNA damage repair processes. Here the authors give mechanistic insights into how TIRR mediates suppression by solving the crystal structure of TIRR bound to the 53BP1 tandem ...
Jiaxu Wang, Zenglin Yuan, Yaqi Cui, Rong Xie, Guang Yang, Muzaffer A. Kassab, Mengxi Wang, Yinliang Ma, Chen Wu, Xiaochun Yu, Xiuhua Liu   +10 more
doaj   +1 more source

Exploring the Management Literature of Sustainable Healthcare: A Bibliometric and Content Analysis

Sustainable Development, EarlyView.
ABSTRACT This study aims to provide a comprehensive overview of sustainable healthcare from the perspective of the management literature. Relevant publications were retrieved from the Scopus database. A total of 85 publications from 1997 to July 2024 were analyzed using the R bibliometrix package. Findings suggest this is a nascent area of study in the
Donna V. Jones, Olaf Weber, Jason Thistlethwaite   +2 more
wiley   +1 more source

Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30. [PDF]

PLoS ONE, 2012
SMN (Survival motor neuron protein) was characterized as a dimethyl-arginine binding protein over ten years ago. TDRD3 (Tudor domain-containing protein 3) and SPF30 (Splicing factor 30 kDa) were found to bind to various methyl-arginine proteins including
Ke Liu, Yahong Guo, Haiping Liu, Chuanbing Bian, Robert Lam, Yongsong Liu, Farrell Mackenzie, Luis Alejandro Rojas, Danny Reinberg, Mark T Bedford, Rui-Ming Xu, Jinrong Min   +11 more
doaj   +1 more source

Immunization and the hepatitis B virus: A view from the ESPGHAN Hepatology Committee. [PDF]

J Pediatr Gastroenterol Nutr
Abstract Hepatitis B virus (HBV) infection remains a global health challenge, with more than 250 million people chronically infected worldwide and >2000 daily deaths from HBV‐related disease. Early‐life acquisition is the primary driver of chronic infection; up to 90% of infants infected perinatally progress to chronic HBV infection compared with ...
Kohlmaier B, Indolfi G, Baumann U, Gonçalves C, Gonzales E, Junge N, Nicastro E, Pop TL, Quintero J, Stephenne X, Tucker B, Doef HV, Waisbourd-Zinman O, Fitzpatrick E.   +13 more
europepmc   +2 more sources

Twin Transition Priorities Within the Sustainable Development Goals and Economic Freedom in the European Union: A Pillar‐Level Analysis

Sustainable Development, EarlyView.
ABSTRACT Europe's twin green and digital transition seeks to align sustainability with digitalization, yet it remains unclear whether progress in twin transition‐relevant SDGs coincides with changes in economic freedom dimensions. Using an EU‐27 panel from 2000 to 2024, we examine the link between the Heritage Index of Economic Freedom and a specific ...
Aura Girlovan, Cristiana Tudor, Isabel‐María García‐Sánchez   +2 more
wiley   +1 more source

“I Stand Out Like a Raven”: Depicting the Female Detective and Tudor History in Nancy Bilyeau’s The Crown

American, British and Canadian Studies Journal, 2017
This article examines the portrayal of female identity and crime in the Tudor period in Nancy Bilyeau’s contemporary historical crime fiction novel, The Crown (2012). Featuring a female detective figure, Joanna Stafford, Bilyeau’s novel forms part of the
Beyer Charlotte
doaj   +1 more source