Results 31 to 40 of about 554 (115)

Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results From the Phase 2 Randomized Trial

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1692-1699, August 2026.
Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava, Michelle Petri, Patrick G. Gavin, Eszter Csomor, Philip Z. Brohawn, Daniel Muthas, Adam Platt, Catharina Lindholm, Nicola Ferrari   +8 more
wiley   +1 more source

Anifrolumab Dose Regimen Selection for a Phase 3 Trial in Lupus Nephritis

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 429-439, August 2026.
In patients with systemic lupus erythematosus (SLE), increased type I interferon signaling is associated with increased disease activity across organs, including in the kidney, which can cause lupus nephritis (LN). Anifrolumab, which abrogates type I interferon signaling, is an approved treatment for moderate to severe SLE.
Joachim Almquist, Yen Lin Chia, Raj Tummala, Lynn Bertagnolli, David Jayne, Weifeng Tang, Catharina Lindholm   +6 more
wiley   +1 more source

Nanofat for Injection Laryngoplasty: Office and Operative Results

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
Nanofat serves as an alternative or adjunct to microfat in patients undergoing injection laryngoplasty. The advantages of nanofat include its favorable safety profile and high procedural and tissue tolerance. There is an absorption rate within one year of 29% which may reduce its effectiveness.
Peak Woo, Anahita Nourmahnad
wiley   +1 more source

Assessing ChatGPT for taxonomic and floristic studies

Nordic Journal of Botany, Volume 2026, Issue 8, August 2026.
The advancement of biological sciences has long been closely linked to technological progress. ChatGPT, a generative artificial intelligence chatbot capable of producing human‐like conversational responses, has recently attracted attention as a potential support tool for scientific research.
Mykyta Peregrym, Olena Kozak, Ahmet Emre Yaprak, Alan Elliott, Pedro Bond Schwartsburd, Karime Abidkulova, Anna Voytsekhovich, Olena Danylevska   +7 more
wiley   +1 more source

Engaging with theoretical models in social science education

Review of Education, Volume 14, Issue 2, August 2026.
Abstract In citizenship education, subjects like social science aim to enhance students' reasoning about social issues through disciplinary knowledge, skills and abilities. One key ability is using theories and models to better understand and reason about societal phenomena.
Johan Sandahl, Patrik Johansson
wiley   +1 more source

Vibrio Community Structure Shapes the Diversity of Carbenicillin‐Hydrolysing Class A β‐Lactamase Circulating in European Coastal Environments

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Vibrio communities shape carbenicillinase diversity in European coasts. Sediments serve as reservoirs of antibiotic‐resistant Vibrio alginolyticus, which can move into the water column and accumulate in bivalves. This spreads β‐lactamase resistance and raises human exposure risks to antibiotic‐resistant pathogenic Vibrio, especially as higher seawater ...
Berenice Reggiardo, Jamal Saad, Marie‐Agnès Travers, Yannick Labreuche, David Goudenège, Eve Toulza, Coralie Broquard, Karl B. Andree, Julia Mougin, Nicolas Argenta, Gaëlle Courtay, Juliette Pouzadoux, Océane Romatif, Audrey Caro, Dolors Furones, Luigi Vezzulli, Gianluca Corno, Andrea Di Cesare, Ignasi Gairin, Bruno Petton, K. Mathias Wegner, Caroline Montagnani, Viviane Boulo, Delphine Destoumieux‐Garzón   +23 more
wiley   +1 more source

In Situ GWAS in Two Range‐Edge Populations of European Beech (Fagus sylvatica L.) Identify Genetic Factors of Adaptation to Climate Change

Molecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT In forest tree populations, the timing of budbreak (TBB) depends on several factors, both environmental and genetic. The genomic architecture underlying this trait is still not fully characterized. So far, common garden experiments have highlighted a few genomic regions with little heritability, while the whole spectrum of TBB variation ...
Lauren Clément, Andrea Modica, Isabelle Lesur Kupin, Christophe Plomion, Catherine Bodénès, Grégoire Le Provost, Sylvie Oddou‐Muratorio, Katrin Heer, Marie Mirouze, Marie‐Christine Carpentier, Bartosz Ulaszewski, William Marande, Jean‐Marc Aury, Simone Duprat, Corinne da Silva, Benjamin Noel, Corinne Cruaud, Karine Labadie, Joëlle Amselem, Johann Confais, Hadi Quesneville, Jean‐André Magdalou, Olivier Panaud, Ivan Scotti   +23 more
wiley   +1 more source

Single-cell microfluidics in combination with chlorophyll a fluorescence measurements to assess the lifetime of the Chlamydomonas PSBO protein. [PDF]

Photosynthetica, 2023
Széles E, Kuntam S, Vidal-Meireles A, Nagy V, Nagy K, ÁBrahám Á, Kovács L, Tóth SZ.   +7 more
europepmc   +1 more source

Letter in reply: indirect treatment comparison of anifrolumab efficacy versus belimumab in adults with systemic lupus erythematosus. [PDF]

J Comp Eff Res, 2023
Bruce IN, Golam S, Steenkamp J, Wang P, Worthington E, Desta B, Psachoulia K, Erhardt W, Tummala R.   +8 more
europepmc   +1 more source

Belimumab or anifrolumab for systemic lupus erythematosus? A risk-benefit assessment. [PDF]

Front Immunol, 2022
Kirou KA, Dall Era M, Aranow C, Anders HJ.   +3 more
europepmc   +1 more source