Results 71 to 80 of about 3,947 (209)
Tumefactive demyelinating lesions: A literature review of recent findings
NeurosciencesTumefactive demyelinating lesion is a variant of multiple sclerosis that is a diagnostic challenge. Tumefactive demyelinating lesion requires extensive work-up as its clinical and radiological features are often indistinguishable from other central ...
Y. Al Malik
semanticscholar +1 more source
Allergy, Volume 80, Issue 10, Page 2738-2754, October 2025.ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco +8 more
wiley +1 more source
Malignancies and IgG4‐related disease
Rheumatology &Autoimmunity, Volume 5, Issue 3, Page 161-173, September 2025.Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley +1 more source
Unusual Manifestation of Immunoglobulin G4-Related Disease Involving the Upper Arm: A Case Report
Journal of the Korean Society of Radiology, 2023 Immunoglobulin G4 (IgG4)-related disease is a rare systemic fibroinflammatory condition characterized by organomegaly or tumefactive lesions associated with lymphoplasmacytic infiltration rich in IgG4 plasma cells.
Jin Hee Park, Sun Joo Lee, Hye Jung Choo
doaj +1 more source
Potential roles of antibodies with different classes in IgG4‐related diseases
Rheumatology &Autoimmunity, Volume 5, Issue 3, Page 174-185, September 2025.This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li +6 more
wiley +1 more source
Recent Updates of Immunoglobulin G4-related Pancreatobiliary Disease
The Korean Journal of Gastroenterology, 2020 Type 1 autoimmune pancreatitis and IgG4-related sclerosing cholangitis (IgG4-SC) are the pancreatobiliary manifestations of IgG4-related disease. IgG4-related disease is a newly named fibroinflammatory condition that is characterized by tumefactive ...
Gyu-Chul Lee , Sung-Hoon Moon
doaj +1 more source
Journal of NeurologyA minority of initial multiple sclerosis (MS) presentations clinically or radiologically resemble other central nervous system (CNS) pathologies, acute disseminated encephalomyelitis (ADEM) or tumefactive demyelination (atypical demyelination ...
Simon Arnett +5 more
semanticscholar +1 more source
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1566-1574, August 2025.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, Volume 12, Issue 11, Page 2376-2377, November 2025.
Raveena Vij +2 more
wiley +1 more source
Frontiers in ImmunologyObjective We present a case of multiple tumefactive demyelinating lesions (TDLs) emerging 24 months after the second cycle of alemtuzumab treatment. Methods A woman with relapsing-remitting multiple sclerosis (MS) discontinued fingolimod treatment due to
Neus Rabaneda-Lombarte +4 more
semanticscholar +1 more source