Results 111 to 120 of about 1,047 (134)

[Tumefactive demyelinating lesion (TDL)].

No shinkei geka. Neurological surgery, 2021
Tumefactive demyelinating lesion(TDL)is defined as a large lesion, size >2 cm, mass effect, perilesional edema and/or ring enhancement. TDL could occur in multiple sclerosis(MS), neuromyelitis optica spectrum disorder(NMOSD), acute disseminated encephalomyelitis(ADEM)or other immunological diseases.
Akihiro, Nakajima, Izumi, Kawachi
openaire   +1 more source

Characterisation of tumefactive demyelinating lesions

Journal of Neurology, Neurosurgery & Psychiatry, 2017
Objectives Tumefactive demyelinating lesions (TDLs) occur spontaneously during the course of MS or as the first manifestation of demyelination and may be precipitated by drug withdrawal, vaccination, viral infection or fingolimod. The objective of this study was to identify the frequency, clinical context and radiological features of TDLs in a ...
Ariadna A Fontes-Villalba, Heath H French, John DE Parratt   +2 more
openaire   +1 more source

Tumefactive demyelinating lesions in children

European Journal of Paediatric Neurology
Tumefactive lesions (TDL) are larger than 2 cm in diameter on T2-weighted brain MRI. They are distinguished from other types of demyelinating lesions by their size and degree of perilesional edema and/or rim enhancement, which can make diagnosis challenging.To study the clinical and radiological features, follow-up and final diagnosis of patients ...
Ayberk Selek, Rahsan Göcmen, Ceren Günbey, Bahadır Konuşkan, Ibrahim Oncel, Banu Anlar   +5 more
openaire   +2 more sources

Tumefactive demyelinating lesion: perfusion-weighted imaging findings

European Journal of Radiology Extra, 2005
Abstract There are so many reports in the literature about MRI findings of multiple sclerosis. Multiple sclerosis usually presents with disseminated plaques of demyelination. But in some cases, it presents with a large, solitary lesion with extensive edema and mass effect that mimic intracranial neoplasms.
PARLAK, MÜFİT, HAKYEMEZ, BAHATTİN, Bozdogan, Erol, Yildiz, Harun, Erdogan, Cuneyt   +4 more
openaire   +2 more sources

Tumefactive demyelinating lesions versus CNS neoplasms, a comparative study

Multiple Sclerosis and Related Disorders, 2023
Differentiating tumefactive demyelinating lesions (TDL) from neoplasms of the central nervous system continues to be a diagnostic dilemma in many cases.Our study aimed to examine and contrast the clinical and radiological characteristics of TDL, high-grade gliomas (HGG) and primary CNS lymphoma (CNSL).This was a retrospective review of 66 patients (23 ...
Sin Hong Chew, Hairuddin Bin Achmad Sankala, Elaine Chew, Md Hanif bin Md Arif, Norzaini Rose Mohd Zain, Hilwati Hashim, Shahedah Binti Koya Kutty, Yong Chuan Chee, Naimah Binti Mohd Saleh, Beng Hooi Ong, Shanthi Viswanathan   +10 more
openaire   +2 more sources

Tumefactive demyelinating lesion

2018
Clinical History: 45-year old man with 7 year history of dysarthria presented in 2018 with clinical worsening. Past MRI showed multiple brain lesions, biopsy showed no tumor cells but was otherwise inconclusive. LP was negative for oligoclonal bands. The patient was diagno...
openaire   +1 more source

Tumefactive demyelination and glioblastoma: a rare collision lesion

Clinical Neuropathology, 2011
Inflammatory demyelination occasionally forms a solitary mass lesion clinically and radiographically indistinguishable from glioma, replete with enhancement and mass effect. Termed "tumefactive demyelination" it often prompts a brain biopsy.We undertook neuroimaging and morphologic analysis of a unifocal demyelinating lesion intimately associated with ...
S F, Roemer, B W, Scheithauer, G G, Varnavas, C F, Lucchinetti   +3 more
openaire   +2 more sources

Spectroscopic magnetic resonance imaging of a tumefactive demyelinating lesion

Neuroradiology, 2002
Tumefactive demyelinating lesions can present with features similar, clinically and radiologically, to those of brain tumours. Proton MR spectroscopy has been increasingly used to characterize intracranial pathology. As the underlying pathophysiology of neoplasms is different from that of demyelinating disease, one may expect the metabolic composition ...
M, Law, D E, Meltzer, S, Cha
openaire   +2 more sources

Tumefactive demyelinating lesions: conventional and advanced magnetic resonance imaging

Multiple Sclerosis Journal, 2005
In rare instances, demyelinating disorders present with radiological features that mimic a brain tumour. This often leads to biopsy, which-apart from carrying significant morbidity-frequently turns out as nondiagnostic or dispensable. We therefore set out to assess the contribution of repeated conventional magnetic resonance imaging (MRI), 1H-MR ...
Christian, Enzinger, Siegrid, Strasser-Fuchs, Stefan, Ropele, Peter, Kapeller, Reinhold, Kleinert, Franz, Fazekas   +5 more
openaire   +2 more sources

Tumefactive demyelinating lesions during etanercept treatment requiring decompressive hemicraniectomy

Multiple Sclerosis Journal, 2012
Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory and immunoregulatory cytokine involved in the pathogenesis of several autoimmune disorders. Etanercept, a TNF-α antagonist (anti-TNF-α) acting as a soluble TNF-α receptor, has been associated with neurological demyelinating disorders.
C W, Cereda, C, Zecca, L, Mazzucchelli, L, Valci, C, Staedler, C L, Bassetti, C, Gobbi   +6 more
openaire   +2 more sources