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Chronic inflammatory demyelinating polyradiculoneuropathy with tumefactive central demyelination
Muscle & Nerve, 2005AbstractA 46‐year‐old man with a 1‐year history of distal paresthesias and mild distal weakness subacutely developed paralysis of the left hand. Electrodiagnostic evaluation revealed a demyelinating peripheral neuropathy that met criteria for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Lisa S, Krivickas +2 more
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Tumefactive demyelination: an approach to diagnosis and management
Journal of Neurology, Neurosurgery & Psychiatry, 2013Tumefactive lesions are an uncommon manifestation of demyelinating disease and can pose a diagnostic challenge in patients without a pre-existing diagnosis of multiple sclerosis. Choosing when to biopsy a tumefactive lesion to exclude alternative pathology can be difficult.
Todd A, Hardy, Jeremy, Chataway
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Acute Tumefactive Inflammatory Demyelination in a Child
Pediatric Neurology, 2011During the course of an afternoon, a previously healthy 6-year-old boy became irritable and complained of rightsided headache. The next day, he developed left facial droop, and 3 days later, left arm and leg weakness. An examination revealed a left lower facial droop, grade 4/5 left arm and leg power, and a left extensor plantar response.
Claire J, Hinnell +3 more
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Tumefactive Demyelination: Glioblastoma
2018At the end of November 2014, a 55-year-old male patient woke up in the morning with, as he described, face slightly distorted towards right and discrete speech disorder. During next few days, he noticed he was slightly clumsy with left hand and leg but without more pronounced motor difficulties.
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Tumefactive demyelinating lesions: A comprehensive review
Multiple Sclerosis and Related Disorders, 2017Tumefactive multiple sclerosis or tumefactive demyelinating lesion (TDL) is one of the rare variants of multiple sclerosis (MS) posing a diagnostic challenge and a therapeutic enigma since it is difficult to distinguish from a true central nervous system (CNS) neoplasm or other CNS lesions on magnetic resonance imaging (MRI).
Hussein, Algahtani +2 more
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Characterisation of tumefactive demyelinating lesions
Journal of Neurology, Neurosurgery & Psychiatry, 2017Objectives Tumefactive demyelinating lesions (TDLs) occur spontaneously during the course of MS or as the first manifestation of demyelination and may be precipitated by drug withdrawal, vaccination, viral infection or fingolimod. The objective of this study was to identify the frequency, clinical context and radiological features of TDLs in a ...
Ariadna A Fontes-Villalba +2 more
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Tumefactive demyelinating lesion
2018Clinical History: 45-year old man with 7 year history of dysarthria presented in 2018 with clinical worsening. Past MRI showed multiple brain lesions, biopsy showed no tumor cells but was otherwise inconclusive. LP was negative for oligoclonal bands. The patient was diagno...
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A Review of Clinical and Imaging Findings in Tumefactive Demyelination
American Journal of Roentgenology, 2021Shotaro Naganawa +2 more
exaly
[Tumefactive Demyelinating Lesions].
Brain and nerve = Shinkei kenkyu no shinpoTumefactive demyelinating lesions (TDL), defined as inflammatory demyelinating lesions, may develop either during treatment for multiple sclerosis and related disorders or as the first demyelinating episode without any past medical history suggesting demyelination. If the latter, it would be so delicate to diagnose as demyelination.
Yuki, Mizumoto, Tetsuya, Abe
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