Results 31 to 40 of about 1,258 (160)

Case Report: A Case of Severe Clinical Deterioration in a Patient With Multiple Sclerosis

Frontiers in Neurology, 2020
Tumefactive multiple sclerosis (MS) is a rare variant of MS that may lead to a rapidly progressive clinical deterioration requiring a multidisciplinary diagnostic workup.
Katharina Breitkopf, Katharina Breitkopf, Katharina Breitkopf, Aykut Aytulun, Moritz Förster, Bastian Kraus, Bernd Turowski, Doreen Huppert, Norbert Goebels, Harald Hefter, Orhan Aktas, Imke Metz, Wolfgang Brück, Guido Reifenberger, Hans-Peter Hartung, Philipp Albrecht   +15 more
doaj   +1 more source

Tumefactive multiple sclerosis lesions under fingolimod treatment [PDF]

Neurology, 2012
Fingolimod is an oral sphingosine 1-phosphate receptor modulator that prevents recirculation of lymphocyte subsets from lymph nodes. It decreases the number of relapses, slows the progression of disability, and improves MRI endpoints in patients with relapsing-remitting multiple sclerosis (RRMS).1 Infrequent but specific side effects are bradycardia ...
Visser, F., Wattjes, M.P., Pouwels, P.J.W., Linssen, W.H.J.P., van Oosten, B.W.   +4 more
openaire   +4 more sources

Tumefactive Multiple Sclerosis Mimicking Neoplasm [PDF]

Acta Chirurgica Latviensis, 2010
Tumefactive Multiple Sclerosis Mimicking Neoplasm Acute demyelination may present as a rapidly expanding space-occupying or tumefactive lesion (TDL). Tumefactive demyelinating lesions are misdiagnosed quite frequently and can result in unnecessary and potentially harmful surgical resection, radiation or toxic chemotherapeutic ...
Liene Elsone, Ardis Platkajis, Guntis Karelis, Sarmite Dzelzite, Maira Murzina   +4 more
openaire   +1 more source

Specific myeloid signatures in peripheral blood differentiate active and rare clinical phenotypes of multiple sclerosis

Frontiers in Immunology, 2023
Current understanding of Multiple Sclerosis (MS) pathophysiology implicates perturbations in adaptive cellular immune responses, predominantly T cells, in Relapsing-Remitting forms (RRMS).
Aigli G. Vakrakou, Aigli G. Vakrakou, Nikolaos Paschalidis, Eleftherios Pavlos, Eleftherios Pavlos, Christina Giannouli, Dimitris Karathanasis, Xristina Tsipota, Georgios Velonakis, Christine Stadelmann-Nessler, Maria-Eleftheria Evangelopoulos, Leonidas Stefanis, Constantinos Kilidireas, Constantinos Kilidireas   +13 more
doaj   +1 more source

Tumefactive multiple sclerosis: an uncommon diagnostic challenge [PDF]

Journal of Chiropractic Medicine, 2011
This case report describes a rare presentation of multiple sclerosis (MS) that was initially diagnosed as a peripheral nerve lesion in the emergency department.A 30-year-old woman presented to a chiropractic teaching clinic with a complaint of a sudden right foot drop.
Martha A, Kaeser, Frank, Scali, Frank P, Lanzisera, Glenn A, Bub, Norman W, Kettner   +4 more
openaire   +2 more sources

Central nervous system tumefactive demyelinating lesions: Risk factors of relapse and follow-up observations

Frontiers in Immunology, 2022
ObjectiveTo track the clinical outcomes in patients who initially presented with tumefactive demyelinating lesions (TDLs), we summarized the clinical characteristics of various etiologies, and identified possible relapse risk factors for TDLs ...
Xinnan Li, Xiuling Miao, Yaming Wang, Junzhao Sun, Haifeng Gao, Jing Han, Yuxin Li, Qingjun Wang, Chenjing Sun, Jianguo Liu   +9 more
doaj   +1 more source

Multiple Large Tumefactive MS Plaques in a Young Man: A Diagnostic Enigma and Therapeutic Challenge

Case Reports in Radiology, 2012
Tumefactive demyelinating lesion is defined as large solitary demyelinating lesion with imaging characteristics mimicking neoplasm. These atypical features include size more than 2 cm, mass effect, edema, and/or ring enhancement.
Hossein Kalanie, Ali Amini Harandi, Reza Bakhshandehpour, Daryoosh Heidari   +3 more
doaj   +1 more source

Immunopathology of Tumefactive Demyelinating Lesions-From Idiopathic to Drug-Related Cases

Frontiers in Neurology, 2022
Tumefactive demyelinating lesions (TDL) represent a diagnostic dilemma for clinicians, and in rare atypical cases a collaboration of a neuroradiologist, a neurologist, and a neuropathologist is warranted for accurate diagnosis.
Aigli G. Vakrakou, Maria-Evgenia Brinia, Ioanna Svolaki, Theodore Argyrakos, Leonidas Stefanis, Constantinos Kilidireas   +5 more
doaj   +1 more source

Identifying Tumefactive Demyelination on Synthetic MRI Myelin Maps. [PDF]

Case Rep Radiol
Tumefactive demyelinating lesions and brain neoplasms often present as a diagnostic challenge due to overlapping radiographic features among conventional imaging modalities ultimately resulting in uncertainty if a biopsy is warranted to establish a definitive diagnosis.
Simons B, Li R, Chandra T, Hayes L.
europepmc   +2 more sources

Serial magnetic resonance imaging changes of pseudotumor lesions in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: a case report

BMC Neurology, 2021
Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy.
Yuying Yan, Shuai Jiang, Ruilin Wang, Xiang Wang, Peng Li, Bo Wu   +5 more
doaj   +1 more source