Results 51 to 60 of about 1,258 (160)

Case Report: Findings Suggestive of Paraclinical Progressive Multifocal Leukoencephalopathy and Lung Cancer-Derived Brain Metastases in an MS Patient Treated With Fingolimod

Frontiers in Neurology, 2021
Fingolimod represents a highly effective disease-modifying drug in patients with active relapsing-remitting multiple sclerosis (RRMS). Its immunosuppressive effects can mediate adverse events like increased risk of cancer development or appearance of ...
Fabian Maass, Philipp von Gottberg, Jonas Franz, Christine Stadelmann, Mathias Bähr, Martin S. Weber, Martin S. Weber   +6 more
doaj   +1 more source

A case of recurrent tumefactive demyelination or tumefactive multiple sclerosis

Sri Lanka Journal of Child Health, 2021
No abstract availableSri Lanka Journal of Child Health, 2021: 50(2): 342 ...
Sachin Damke, Sham Balkisanji Lohiya, Bhavana Lakhkar   +2 more
openaire   +2 more sources

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1566-1574, August 2025.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

Tumefactive multiple sclerosis requiring emergent biopsy and histological investigation to confirm the diagnosis: a case report

Journal of Medical Case Reports, 2012
Introduction Tumefactive multiple sclerosis is a demyelinating disease that demonstrates tumor-like features on magnetic resonance imaging. Although diagnostic challenges without biopsy have been tried by employing radiological studies and cerebrospinal ...
Yamada So, Yamada Shoko, Nakaguchi Hiroshi, Murakami Mineko, Hoya Katsumi, Matsuno Akira, Yamazaki Kazuto, Ishida Yasuo   +7 more
doaj   +1 more source

7 Tesla MRI in Multiple Sclerosis: Insights From Its Use in Clinical Routine

European Journal of Neurology, Volume 32, Issue 8, August 2025.
Insights from the impact of 7T MRI in routine clinical care in patients with not yet clearly defined neuro‐inflammatory disorders of the central nervous system or in MS patients with uncertainties during routine clinical care. ABSTRACT Background 7 Tesla (7 T) magnetic resonance imaging (MRI) offers higher spatial resolution and signal‐to‐noise ratio ...
A. León Betancourt, F. Messmer, A. Chan, R. Wiest, G. Bonanno, M. Capiglioni, R. Hoepner, F. Wagner, H. Hammer, P. Radojewski   +9 more
wiley   +1 more source

The effect of ocrelizumab on Balo's tumefactive lesion: A case report

Radiology Case Reports
Balo's concentric sclerosis (BCS) is a rare subtype of multiple sclerosis. Advanced MRI metrics, such as magnetization transfer ratio (MTR), fractional anisotropy (FA), mean diffusivity (MD), and the ratio of total N-acetylaspartate concentration/total ...
Muhammad Faraz Raghib, MD, Fen Bao, MS, Sophia Tessema, MD, Carla Santiago Martinez, MS, Jacob Rube, MD, Evanthia Bernitsas, MD   +5 more
doaj   +1 more source

Clinical impact and safety of brain biopsy in unexplained central nervous system disorders: a real‐world cohort study

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 792-804, April 2025.
Abstract Objective A substantial part of central nervous system (CNS) disorders remains unexplained, despite various new and minimally invasive diagnostic techniques. Within this rapidly developing diagnostic field, the precise role of brain biopsy is unknown.
Robin W. van Steenhoven, Saan Salih, Juna M. de Vries, Ide Smets, Rob M. Verdijk, Mayke Gardeniers, Jeroen Kerstens, Juliette Brenner, Yvette S. Crijnen, Marjolein Geurts, Jacoline E. C. Bromberg, Corine H. GeurtsvanKessel, Peter A. E. Sillevis Smitt, Rutger K. Balvers, Maarten J. Titulaer   +14 more
wiley   +1 more source

Multiple Sclerosis and Oligodendroglioma: An Exceptional Association

Case Reports in Neurological Medicine, 2014
The cooccurrence of multiple sclerosis (MS) and oligodendroglioma is very rare. We present a 43-year-old male patient with the diagnosis of MS lasting for 14 years who developed seizures and right hemiparesis; cerebral MRI revealed an already known ...
Ana Teresa Carvalho, Paulo Linhares, Lígia Castro, Maria José Sá   +3 more
doaj   +1 more source

Severe tumefactive rebound of multiple sclerosis following fingolimod cessation [PDF]

BMJ Case Reports, 2016
Fingolimod is an oral sphingosine-1-phosphate receptor modulator approved for the treatment of active relapsing-remitting multiple sclerosis (RRMS). Recent reports have highlighted the possible risk of rebound disease activity after withdrawal of fingolimod.
Sharfaraz, Salam, Tatiana, Mihalova, Rekha, Siripurapu   +2 more
openaire   +2 more sources

Letter on “Real‐World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell‐Based Assay”

Annals of Clinical and Translational Neurology, Volume 12, Issue 11, Page 2376-2377, November 2025.
Raveena Vij, Alexander J. Jonokuchi, Ilya Kister   +2 more
wiley   +1 more source