Results 61 to 70 of about 1,258 (160)

Multifaceted Biomarkers Suggest a Similar Profile of CNS Pathology in Relapsing and Progressive MS

European Journal of Neurology, Volume 32, Issue 2, February 2025.
ABSTRACT Background Relapsing–remitting (RR) and primary progressive (PP) multiple sclerosis (MS) have distinct clinical courses, but underlying pathophysiological differences remain unclear. We compared pathological components between RRMS, PPMS, and other inflammatory and neurodegenerative disorders, leveraging soluble biomarkers and post‐mortem ...
Katelijn M. Blok, Romy A. M. Klein Kranenbarg, Kirtana Ananth, Hendrik J. Engelenburg, Aletta van den Bosch, Lucia A. A. Giannini, Janet de Beukelaar, Harro Seelaar, Inge Huitinga, Ari Green, Beatrijs Wokke, Ahmed Abdelhak, Joost Smolders   +12 more
wiley   +1 more source

The Neuroimaging Spectrum of Neurosarcoidosis

Clinical Neuroimaging, Volume 2, Issue 1, 2025.
ABSTRACT Among its many forms, involvement of the nervous system in sarcoidosis ranks as one of the most severe and potentially disabling manifestations of the disease, and timely recognition and accurate diagnosis are critical for its optimal treatment.
Spencer K. Hutto, Gabriela A. Bou
wiley   +1 more source

Clinico-radiologic features and therapeutic strategies in tumefactive demyelination: a retrospective analysis of 50 consecutive cases

Therapeutic Advances in Neurological Disorders, 2021
Aims: Our goal was to expand the spectrum of clinico-radiologic characteristics and the possible therapeutic choices in patients with tumefactive demyelinating lesions (TDLs).
Aigli G. Vakrakou, Dimitrios Tzanetakos, Maria-Eleptheria Evangelopoulos, Theodore Argyrakos, John S. Tzartos, Maria Anagnostouli, Elissavet Andreadou, Georgios Koutsis, Georgios Velonakis, Panagiotis Toulas, Elias Gialafos, Antonios Dimitrakopoulos, Erasmia Psimenou, Leonidas Stefanis, Constantinos Kilidireas   +14 more
doaj   +1 more source

MS Variants (ORP-38) [PDF]

Neurology Letters, 2023
In this lecture, multiple sclerosis variants will be discussed, which include Solitary Sclerosis, Schilder's disease, Baló's concentric sclerosis, Marburg variant of multiple sclerosis.
Ebrahim Kouchaki
doaj  

Chronic active lesions preferentially localize in watershed territories in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 11, Issue 11, Page 2912-2922, November 2024.
Abstract Objective Paramagnetic rim lesions (PRLs) are a biomarker of chronic active lesions (CALs), and an important driver of neurological disability in multiple sclerosis (MS). The reason subtending some acute lesions evolvement into CALs is not known. Here we ask whether a relatively lower oxygen content is linked to CALs.
Ahmad A. Toubasi, Jarrod J. Eisma, Jiacheng Wang, Habeeb F. Kazimuddin, Bryan Hernandez, Taegan Vinarsky, Caroline Gheen, Zachary Rohm, Carynn Koch, Margareta A. Clarke, Rachael Cheek, John Kramer, James Eaton, Manus J. Donahue, Francesca Bagnato   +14 more
wiley   +1 more source

Myelinoclastic diffuse sclerosis (Schilder’s disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures

Journal of Neuroinflammation, 2019
Background Myelinoclastic diffuse sclerosis (MDS; also termed Schilder’s disease) is a rare inflammatory demyelinating disorder of the central nervous system characterised by demyelination of vast areas of the white matter. It is unclear whether MDS is a
S. Jarius, J. Haas, F. Paul, B. Wildemann   +3 more
doaj   +1 more source

Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody‐associated Disease, Aquaporin‐4 Antibody‐Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis

Annals of Neurology, Volume 96, Issue 2, Page 276-288, August 2024.
Objective To evaluate: (1) the distribution of gray matter (GM) atrophy in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), aquaporin‐4 antibody‐positive neuromyelitis optica spectrum disorder (AQP4+NMOSD), and relapsing–remitting multiple sclerosis (RRMS); and (2) the relationship between GM volumes and white matter lesions in ...
Rosa Cortese, Marco Battaglini, Ferran Prados, Giordano Gentile, Ludovico Luchetti, Alessia Bianchi, Lukas Haider, Anu Jacob, Jacqueline Palace, Silvia Messina, Friedemann Paul, Romain Marignier, Françoise Durand‐Dubief, Carolina de Medeiros Rimkus, Samira Luisa Apostolos Pereira, Douglas Kazutoshi Sato, Massimo Filippi, Maria Assunta Rocca, Laura Cacciaguerra, Àlex Rovira, Jaume Sastre‐Garriga, Georgina Arrambide, Yaou Liu, Yunyun Duan, Claudio Gasperini, Carla Tortorella, Serena Ruggieri, Maria Pia Amato, Monica Ulivelli, Sergiu Groppa, Matthias Grothe, Sara Llufriu, Maria Sepulveda, Carsten Lukas, Barbara Bellenberg, Ruth Schneider, Piotr Sowa, Elisabeth G. Celius, Anne‐Katrin Pröbstel, Cristina Granziera, Özgür Yaldizli, Jannis Müller, Bruno Stankoff, Benedetta Bodini, Frederik Barkhof, Olga Ciccarelli, Nicola De Stefano, for the MAGNIMS Study Group, F. Barkhof, N. de Stefano, J. Sastre‐Garriga, O. Ciccarelli, C. Enzinger, M. Filippi, Claudio Gasperini, L. Kappos, J. Palace, H. Vrenken, À. Rovira, M.A. Rocca, T. Yousry   +60 more
wiley   +1 more source

Fulminant demyelinating disease of the central nervous system effectively treated with a combination of decompressive craniectomy and immunotherapy: A case report and literature review

Clinical Case Reports, Volume 12, Issue 7, July 2024.
Key Clinical Message Accurately identifying fulminant demyelinating diseases is important for sudden onset of asymmetric cerebral white matter lesions with mass effect. Initially, immunotherapy should be administered; however, surgical intervention should be performed with poor response to medical management and evident signs of cerebral herniation ...
Toshihiro Ide, Ryo Ebashi, Makoto Eriguchi, Shinichi Aishima, Tatsuya Abe, Hideo Hara   +5 more
wiley   +1 more source

A Tumefactive Multiple Sclerosis Case Mimicking a Focal Cerebral Mass

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Tumefactive multiple sclerosis is a rare demyelinating disease presenting with a focal cerebral mass. Clinically and radiographically, the disease is usually difficult to differentiate from a tumor and abscess.
Olcay Unver, Zehra Isik Hasiloglu, Umut Durak, Serap Uysal   +3 more
doaj  

Neuroimaging of tumefactive multiple sclerosis with atypical features

Radiology Case Reports, 2012
Tumefactive demyelinating lesions or tumefactive multiple sclerosis (TMS) constitute a unique presentation of demyelinating disease that frequently mimics intracranial neoplasm, infection or other, nondemyelinating intracranial pathology. Consequently, these lesions, which are larger than typical multiple sclerosis plaques and are generally ...
Koppula, Rohit, Degnan, Andrew J., Ghassibi, Mark, Duggan, Peter, Jones, Robert, Levy, Lucien M.   +5 more
openaire   +2 more sources