Results 131 to 140 of about 6,418,846 (364)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Understanding the tumor immune microenvironment (TIME) for effective therapy

Nature Network Boston, 2018
M. Binnewies, Edward W. Roberts, K. Kersten, Vincent Chan, Douglas Fearon, M. Merad, L. Coussens, D. Gabrilovich, S. Ostrand-Rosenberg, S. Ostrand-Rosenberg, C. Hedrick, R. Vonderheide, M. Pittet, R. Jain, W. Zou, T. Howcroft, E. Woodhouse, R. Weinberg, M. Krummel   +18 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Clinicopathological observation and prognostic factors of invasive breast cancer with medullary in Xinjiang

BMC Medical Informatics and Decision Making
Background Invasive breast cancer (BC) with medullary is a special type of BC, accounting for 3 ~ 6% of invasive BC. To investigate clinicopathological characteristics concerning invasive BC with medullary in Xinjiang area and analyze the prognostic ...
Yan Li, Xiaoping Ma, Zhenhui Zhao, Li Li, Chunyan Gao, Dan Liu, Bingyu Li, Bing Zhao   +7 more
doaj   +1 more source

The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)

IEEE Transactions on Medical Imaging, 2015
Bjoern H Menze, A. Jakab, S. Bauer, Jayashree Kalpathy-Cramer, K. Farahani, J. Kirby, Y. Burren, N. Porz, J. Slotboom, R. Wiest, L. Lanczi, E. Gerstner, M. Weber, T. Arbel, B. Avants, N. Ayache, Patricia Buendia, D. Collins, Nicolas Cordier, Jason J. Corso, A. Criminisi, T. Das, H. Delingette, Çağatay Demiralp, C. Durst, M. Dojat, Senan Doyle, Joana Festa, F. Forbes, Ezequiel Geremia, B. Glocker, P. Golland, Xiaotao Guo, A. Hamamci, K. Iftekharuddin, R. Jena, N. John, E. Konukoglu, D. Lashkari, J. Mariz, Raphael Meier, Sérgio Pereira, Doina Precup, S. Price, Tammy Riklin-Raviv, Syed M. S. Reza, Michael T. Ryan, Duygu Sarikaya, L. Schwartz, Hoo-Chang Shin, J. Shotton, Carlos Alberto Silva, N. Sousa, N. Subbanna, G. Székely, Thomas J. Taylor, O. Thomas, N. Tustison, Gözde B. Ünal, F. Vasseur, M. Wintermark, Dong Hye Ye, Liang Zhao, Binsheng Zhao, Darko Zikic, M. Prastawa, M. Reyes, K. V. Leemput   +67 more
semanticscholar   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

JACKSONIAN EPILEPSY; TREPHINING; REMOVAL OF SMALL TUMOR, AND EXCISION OF CORTEX [PDF]

, 1891
CHARLES K. MILLS, W. W. Keen
openalex   +1 more source

Autonomic modulation of the immune response and implications for CNS malignancies

npj Precision Oncology
While the central nervous system (CNS) has long been known to regulate global physiologic processes, its role in regulating immune responses has only relatively recently been appreciated.
Lucas P. Wachsmuth, Ethan S. Srinivasan, Bhairavy J. Puviindran, Aden P. Haskell-Mendoza, Tyrone DeSpenza, Peter E. Fecci   +5 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

THE DURATION AND EXTENT OF INDUCED RESISTANCE TOWARD TUMOR TRANSPLANTATION IN MICE [PDF]

, 1912
William H. Woglom
openalex   +1 more source