Results 171 to 180 of about 8,763,296 (354)

Clinical utility of therapy selection informed by predicted nonresponse to tumor necrosis factor-ɑ inhibitors: an analysis from the Study to Accelerate Information of Molecular Signatures (AIMS) in rheumatoid arthritis [PDF]

, 2021
Vibeke Strand, Stanley Cohen, Jeffrey R. Curtis, Lixia Zhang, Alan Kivitz, Robert W. Levin, Angela Mathis, Erin Connolly-Strong, Johanna B. Withers   +8 more
openalex   +1 more source

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Proceedings of the National Academy of Sciences of the United States of America, 2001
T. Sørlie, C. Perou, R. Tibshirani, T. Aas, S. Geisler, H. Johnsen, T. Hastie, M. Eisen, M. van de Rijn, S. Jeffrey, T. Thorsen, H. Quist, J. Matese, P. Brown, D. Botstein, P. Lønning, A. Børresen-Dale   +16 more
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab [PDF]

, 2023
Arash Nabbi, Arnavaz Danesh, Osvaldo Espin‐Garcia, Stephanie Pedersen, Johanna Wellum, Lingyan Helen Fu, Joseph N. Paulson, Birgit Geoerger, Lynley V. Marshall, Tanya Trippett, Gianluca Rossato, Trevor J. Pugh, Katherine E. Hutchinson   +12 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor [PDF]

, 2006
Anne Thoustrup Saber, Nicklas Raun Jacobsen, Jette Bornholdt, Sanna L. Kjær, Marianne Dybdahl, Lotte Risom, Steffen Loft, Ulla Vogel, Håkan Wallin   +8 more
openalex   +1 more source

BGF-YOLO: Enhanced YOLOv8 with Multiscale Attentional Feature Fusion for Brain Tumor Detection [PDF]

, 2023
Ming Kang, Chee‐Ming Ting, Fung Fung Ting, Raphaël C. -W. Phan   +3 more
openalex   +1 more source

Microenvironmental regulation of tumor progression and metastasis

Nature Network Boston, 2013
D. Quail, J. Joyce
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source