Results 241 to 250 of about 3,691,927 (315)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer. [PDF]
Pigment Cell Melanoma ResJin X, Zhang Y, Zhu Y, Zhang Z, Shi C.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Impact of tumor budding on recurrence risk prediction in stage I-III colorectal cancer: a Swedish cohort study. [PDF]
Am J Clin PatholBarot S +7 more
europepmc +1 more source
Framework for Statistical Parametric Mapping of the Interactions between Glioblastoma Location, Treatment, Prognostic Variables, and Survival Using a Phase III Trial. [PDF]
Clin Cancer ResSanvito F +14 more
europepmc +1 more source
Bilateral Gonadoblastoma in a 12-Year-Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case. [PDF]
Clin Case RepQuraish A +4 more
europepmc +1 more source