Results 251 to 260 of about 6,418,846 (364)

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

Molecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Smooth Muscle Tumors of the Alimentary Canal

, 1956
John H. Morton, Samuel J. Stabins, John J. Morton   +2 more
openalex   +2 more sources

Innate and adaptive immune cells in the tumor microenvironment

Nature Immunology, 2013
T. Gajewski, H. Schreiber, yang-xin fu
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Adrenalin Producing Tumors in Childhood

, 1956
Thomas C. Moore, Harris B. Shumacker
openalex   +2 more sources

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

Cell, 2017
N. Mcgranahan, C. Swanton
semanticscholar   +1 more source

Tumor-draining lymph nodes respond to immune checkpoint inhibition and orchestrate tumor immune remodeling. [PDF]

Cancer Immunol Immunother
Zhang J, Ma J, Niu Y, Liu J, Wang Z, Guo J, Meng Y, Sun R, Zhang Z, Liu H, Xu J, Zan L, Guan X, Wang X.   +13 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A CASE OF DOUBLE MALIGNANT TUMORS, CARCINOMA OF THE PROSTATE AND THE URINARY BLADDER IN A SINGLE PATIENT

, 1952
Shinji Ito
openalex   +2 more sources

Decoding tumor-stroma interactions: from molecular crosstalk to therapeutic targets. [PDF]

FEBS Open Bio
Fabregat I.
europepmc   +1 more source