Results 21 to 30 of about 8,099,813 (387)

Risk factors for developing high-output ileostomy in CRC patients: a retrospective study

open access: yesBMC Surgery, 2021
Background Anastomotic leakage is one of the most serious postoperative complications of rectal cancer. Prophylactic ileostomy has been widely used to reduce the risk and severity of complications of anastomotic leakage.
Dongxiao Bai   +9 more
doaj   +1 more source

Tumor angiogenesis

open access: yesAdvances in Cancer Research, 2020
The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that
Farah Fatmawati, Whendy Wijaksono
semanticscholar   +1 more source

PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOS

open access: yesJournal of Translational Medicine, 2023
Background Gastric cancer (GC) is the fifth most common cancer and the third most common cause of cancer death worldwide. Plant homeodomain (PHD)-finger domain protein PHF5A has been demonstrated to play a promoting role in a variety of cancers.
Zhandong Zhang   +5 more
doaj   +1 more source

Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives

open access: yesMolecular Cancer, 2021
Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin, phenotypic and functional heterogeneity, are the most essential components of the tumor microenvironment (TME).
Xiaoqi Mao   +9 more
semanticscholar   +1 more source

Expert consensus on population-based BRCA germline mutation screening in China (2024 edition) [PDF]

open access: yesZhongguo aizheng zazhi
Germline mutations in BRCA genes (including BRCA1/2) are the major risk factors for hereditary tumors including breast and ovarian cancer. Population based BRCA gene screening, particularly in high-risk individuals with a family history of cancer, can ...
China Anti-Cancer Association Tumor Biomarker Professional Committee, Shanghai Anti-Cancer Association Tumor Biomarker Professional Committee
doaj   +1 more source

TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells.

open access: yesCancer Research, 2017
Recent clinical successes of cancer immunotherapy necessitate the investigation of the interaction between malignant cells and the host immune system. However, elucidation of complex tumor-immune interactions presents major computational and experimental
Taiwen Li   +7 more
semanticscholar   +1 more source

Indocyanine green near-infrared imaging-guided lymph node dissection during oesophageal cancer surgery: A single-centre experience

open access: yesFrontiers in Surgery, 2023
ObjectiveThis study aimed to investigate the feasibility of using indocyanine green (ICG) near-infrared (NIR) imaging during lymphadenectomy for oesophageal cancer.MethodsEighty-seven patients with primary oesophageal cancer were enrolled in this study ...
Saihua Chen   +9 more
doaj   +1 more source

Inhibiting PRMT5 induces DNA damage and increases anti-proliferative activity of Niraparib, a PARP inhibitor, in models of breast and ovarian cancer

open access: yesBMC Cancer, 2023
Background Inhibitors of Poly (ADP-Ribose) Polymerases (PARP) provide clinical benefit to patients with breast and ovarian cancers, by compromising the DNA repair activity of cancer cells.
Shane O’Brien   +8 more
doaj   +1 more source

Myeloid-Derived Suppressor Cells and CD68+CD163+M2-Like Macrophages as Therapeutic Response Biomarkers Are Associated with Plasma Inflammatory Cytokines: A Preliminary Study for Non-Small Cell Lung Cancer Patients in Radiotherapy

open access: yesJournal of Immunology Research, 2022
Background. Recent studies show that myeloid-derived suppressor cells (MDSCs) and M2-like macrophages are involved in the treatment of tumors; however, their therapeutic response role is rarely known in non-small cell lung cancer (NSCLC) during ...
Minghe Lv   +7 more
doaj   +1 more source

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

open access: yesScientific Reports, 2017
Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this signaling in tumors that lack primary cilia, and find that IFT20 mediates
M. Nishita   +11 more
semanticscholar   +1 more source

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