Results 21 to 30 of about 8,763,296 (354)

Myeloid-Derived Suppressor Cells and CD68+CD163+M2-Like Macrophages as Therapeutic Response Biomarkers Are Associated with Plasma Inflammatory Cytokines: A Preliminary Study for Non-Small Cell Lung Cancer Patients in Radiotherapy

Journal of Immunology Research, 2022
Background. Recent studies show that myeloid-derived suppressor cells (MDSCs) and M2-like macrophages are involved in the treatment of tumors; however, their therapeutic response role is rarely known in non-small cell lung cancer (NSCLC) during ...
Minghe Lv, Xibing Zhuang, Shali Shao, Xuan Li, Yunfeng Cheng, Duojiao Wu, Xiangdong Wang, Tiankui Qiao   +7 more
doaj   +1 more source

Diffusion Tensor Imaging for Assessment of Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer. [PDF]

, 2016
In this study, the prognostic significance of tumor metrics derived from diffusion tensor imaging (DTI) was evaluated in patients with locally advanced breast cancer undergoing neoadjuvant therapy.
Harnish, Roy, Hylton, Nola M, Li, Wen, Newitt, David C, Proctor, Evelyn, Shin, Hee Jung, Wilmes, Lisa J   +6 more
core   +1 more source

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

Scientific Reports, 2017
Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this signaling in tumors that lack primary cilia, and find that IFT20 mediates
M. Nishita, Seung-Yeol Park, T. Nishio, Koki Kamizaki, Zhichao Wang, Kota Tamada, T. Takumi, Ryuju Hashimoto, H. Otani, G. Pazour, V. Hsu, Y. Minami   +11 more
semanticscholar   +1 more source

Feasibility of dendritic cell-based vaccine against glioblastoma by using cytoplasmic transduction peptide (CTP)-fused protein antigens combined with anti-PD1

Human Vaccines & Immunotherapeutics, 2020
Recent clinical trials utilizing antigen-pulsed dendritic cells (DCs) have demonstrated increased survival of vaccinated cancer patients. Besides, the cytoplasmic transduction peptide (CTP) not only has an excellent transcellular efficiency but also ...
Young-Hee Kim, Thi-Anh-Thuy Tran, Thi-Hoang-Oanh Duong, Shin Jung, In-Young Kim, Kyung-Sub Moon, Woo-Youl Jang, Hyun-Ju Lee, Je-Jung Lee, Tae-Young Jung   +9 more
doaj   +1 more source

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells [PDF]

, 2018
While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents.
Chen, Andy, Fan, Yao, Jalali, Aydin, Li, Bai-Yan, Liu, Shengzhi, Minami, Kazumasa, Nakshatri, Harikrishna, Ogawa, Kazuhiko, Yokota, Hiroki   +8 more
core   +1 more source

Sentinel Lymph Node Status is a Main Prognostic Parameter Needful for the Correct Staging of Patients with Melanoma Thicker than 4 mm: Single-Institution Experience and Literature Meta-Analysis

Journal of Investigative Surgery, 2019
Purpose of the study: The usefulness of sentinel lymph node biopsy in thick melanomas is debated. The aim of this study was to evaluate the possible prognostic significance of sentinel lymph node biopsy in T4 melanoma patients and to verify whether this ...
Borgognoni L, Sestini S, Gerlini G, Brandani P, Chiarugi C, Gelli R, Giannotti V, Crocetti E   +7 more
doaj   +1 more source

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

Journal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

Expression of Programmed Cell Death 1 and Lymphocyte Activation Gene 3 in Perioperation of Adenocarcinoma of Esophagogastric Junction and Related Significance

Zhongliu Fangzhi Yanjiu, 2019
Objective To evaluate the expression of programmed cell death 1 (PD-1) and lymphocyte activation gene 3 (LAG-3) in lymphocytes following surgery for advanced adenocarcinoma of esophagogastric junction(AEGJ), and to understand the effect of radical ...
ZHANG Wei, LI Shoumiao, GONG Yanxin, LI Baozhong, ZHANG Zhizhong, LIU Zhiqiang   +5 more
doaj   +1 more source

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

Science, 2020
Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear.
D. Nejman, Ilana Livyatan, Garold Fuks, N. Gavert, Yaara Zwang, L. Geller, Aviva Rotter-Maskowitz, Roi Weiser, Giuseppe Mallel, Elinor Gigi, A. Meltser, G. Douglas, I. Kamer, V. Gopalakrishnan, T. Dadosh, S. Levin-Zaidman, S. Avnet, Tehila Atlan, Z. Cooper, R. Arora, Alexandria P. Cogdill, M. A. W. Khan, G. Ologun, Yuval Bussi, A. Weinberger, M. Lotan-Pompan, O. Golani, G. Perry, Merav Rokah, K. Bahar-Shany, E. Rozeman, C. Blank, Anat Ronai, R. Shaoul, A. Amit, Tatiana Dorfman, R. Kremer, Z. Cohen, S. Harnof, T. Siegal, E. Yehuda‐Shnaidman, E. Gal-Yam, H. Shapira, N. Baldini, M. Langille, A. Ben-nun, B. Kaufman, A. Nissan, T. Golan, M. Dadiani, Keren Levanon, J. Bar, S. Yust-Katz, I. Barshack, D. Peeper, D. Raz, E. Segal, J. Wargo, J. Sandbank, N. Shental, R. Straussman   +60 more
semanticscholar   +1 more source

Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis

Cancer Cell International, 2021
Background Osteosarcoma (OS) is the most common primary malignant bone tumor in young people. Tumor-associated macrophages (TAMs) have been reported to play an important role in the development of osteosarcoma.
Hongliang Zhang, Yiyang Yu, Jun Wang, Yu Han, Tingting Ren, Yi Huang, Chenglong Chen, Qingshan Huang, Wei Wang, Jianfang Niu, Jingbing Lou, Wei Guo   +11 more
doaj   +1 more source