Results 41 to 50 of about 4,164,410 (317)

Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin

open access: yesMolecular Cancer, 2021
Background Cis-diamminedichloro-platinum (CDDP)-based chemotherapy regimens are the most predominant treatment strategies for patients with esophageal squamous cell carcinoma (ESCC).
Yunlong Jia   +11 more
doaj   +1 more source

Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck [PDF]

open access: yes, 2006
Background The proto-oncogene pituitary tumor-transforming gene (PTTG) has been shown to be abundantly overexpressed in a large variety of neoplasms likely promoting neo-vascularization and tumor invasiveness.
Solbach, Christine   +14 more
core   +2 more sources

The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

open access: yesCell Death Discovery, 2023
CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1
Jingbing Lou   +10 more
doaj   +1 more source

Mathematical modeling of tumor growth and treatment [PDF]

open access: yes, 2014
Using mathematical models to simulate dynamic biological processes has a long history. Over the past couple of decades or so, quantitative approaches have also made their way into cancer research.
Chaplain, Mark A. J.   +2 more
core   +1 more source

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

open access: yesJournal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic [PDF]

open access: yes, 2011
Conventional cancer therapies are often limited in effectiveness and exhibit strong side effects. Therefore, alternative therapeutic strategies are demanded.
Igor V. Deyneko   +16 more
core   +1 more source

The Role of Metabolic Plasticity of Tumor-Associated Macrophages in Shaping the Tumor Microenvironment Immunity

open access: yes, 2022
SIMPLE SUMMARY: Tumor associated macrophages (TAMs) support disease progression by providing tumor cells cytokines and chemokines necessary for malignant growth and nutrient support. In the tumor microenvironment (TME), TAMs often rewire their metabolism
Md Nabiul Hasan   +7 more
core   +1 more source

New molecular mediators in tumor angiogenesis [PDF]

open access: yes, 2007
Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Jonas, Dietger   +2 more
core   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

open access: yes, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Surgical Treatment and Proposed Modified Classification for Harrington Class III Periacetabular Metastases

open access: yesOrthopaedic Surgery, 2021
Objectives This study aims to: (i) evaluate the outcome of patients with Harrington class III lesions who were treated according to Harrington classification; (ii) propose a modified surgical classification for Harrington class III lesions; and (iii ...
Ran Wei   +6 more
doaj   +1 more source

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