Results 21 to 30 of about 2,831,620 (267)

Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis

Cancer Cell International, 2021
Background Osteosarcoma (OS) is the most common primary malignant bone tumor in young people. Tumor-associated macrophages (TAMs) have been reported to play an important role in the development of osteosarcoma.
Hongliang Zhang, Yiyang Yu, Jun Wang, Yu Han, Tingting Ren, Yi Huang, Chenglong Chen, Qingshan Huang, Wei Wang, Jianfang Niu, Jingbing Lou, Wei Guo   +11 more
doaj   +1 more source

RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

Journal of Translational Medicine, 2022
Background Targeting glutamine metabolism is previously indicated as a potential and attractive strategy for gastric cancer (GC) therapy. However, the underlying mechanisms responsible for the modification of glutamine metabolism in GC cells have not ...
Haofeng Liu, Qiu Xue, Hongzhou Cai, Xiaohui Jiang, Guangxin Cao, Tie Chen, Yuan Chen, Ding Wang   +7 more
doaj   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

Malaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson   +8 more
doaj   +1 more source

Brain Tumors [PDF]

Seminars in Nuclear Medicine, 2012
This review addresses the specific contributions of nuclear medicine techniques, and especially positron emission tomography (PET), for diagnosis and management of brain tumors. (18)F-Fluorodeoxyglucose PET has particular strengths in predicting prognosis and differentiating cerebral lymphoma from nonmalignant lesions.
Herholz, Karl; id_orcid 0000-0002-8658-0151, Langen, Karl Josef, Schiepers, Christiaan, Mountz, James M.   +3 more
openaire   +3 more sources

The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

Cell Death Discovery, 2023
CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1
Jingbing Lou, Hongliang Zhang, Qingshan Huang, Chenglong Chen, Wei Wang, Jianfang Niu, Jiuhui Xu, Tingting Ren, Yi Huang, Xiaodong Tang, Wei Guo   +10 more
doaj   +1 more source

Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin

Molecular Cancer, 2021
Background Cis-diamminedichloro-platinum (CDDP)-based chemotherapy regimens are the most predominant treatment strategies for patients with esophageal squamous cell carcinoma (ESCC).
Yunlong Jia, Cong Tian, Hongyan Wang, Fan Yu, Wei Lv, Yuqing Duan, Zishuo Cheng, Xuexiao Wang, Yu Wang, Tianxu Liu, Jiali Wang, Lihua Liu   +11 more
doaj   +1 more source

Surgical Treatment and Proposed Modified Classification for Harrington Class III Periacetabular Metastases

Orthopaedic Surgery, 2021
Objectives This study aims to: (i) evaluate the outcome of patients with Harrington class III lesions who were treated according to Harrington classification; (ii) propose a modified surgical classification for Harrington class III lesions; and (iii ...
Ran Wei, Chiao Yee Lim, Yi Yang, Xiao‐dong Tang, Tai‐qiang Yan, Rong‐li Yang, Wei Guo   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Tumor neoantigens and tumor immunotherapies

AGING MEDICINE
AbstractAs a high‐risk group of patients with cancer, the elderly exhibit limited efficacy with traditional treatments. Immunotherapy emerges as a promising adjunctive therapeutic approach that holds potential in addressing the needs of geriatric patients with cancer.
Wang Jiani, Tan Qin, Ma Jie
openaire   +3 more sources

Tumor Promotion by Tumor-Associated Macrophages

, 2007
Recent years have seen a renaissance of the inflammation-cancer connection stemming from different lines of work and leading to a generally accepted paradigm (Balkwill and Mantovani 2001; Mantovani et al. 2002; Coussens and Werb 2002; Balkwill et al. 2005).
PORTA, Chiara, Subhra Kumar B, Larghi P, Rubino L, Mancino A, SICA, Antonio   +5 more
openaire   +4 more sources