Results 41 to 50 of about 8,099,813 (387)

Tumor to Tumor Metastasis: A Case Report

Journal of Nepal Medical Association, 2021
Colon carcinoma spreads locally around the intestine wall and can undergo distant metastasis via the hematogenous or lymphatic spread. It rarely metastasizes to the female genital tract and is not fully reported to involve a uterine leiomyoma. Herein we report such an unusual case of a 27 years female a known case of sigmoid colon adenocarcinoma who ...
Diksha Karki, Purbesh Adhikari, Dipti Shrestha, Anil Kafle   +3 more
openaire   +3 more sources

The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

Cell Death Discovery, 2023
CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1
Jingbing Lou, Hongliang Zhang, Qingshan Huang, Chenglong Chen, Wei Wang, Jianfang Niu, Jiuhui Xu, Tingting Ren, Yi Huang, Xiaodong Tang, Wei Guo   +10 more
doaj   +1 more source

Macrophage Polarization States in the Tumor Microenvironment

International Journal of Molecular Sciences, 2021
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages are historically regarded as anti-tumor, while M2-polarized macrophages, commonly deemed tumor-associated macrophages (TAMs), are contributors to many pro-tumorigenic ...
Ava J Boutilier, Sherine F. Elsawa
semanticscholar   +1 more source

Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. [PDF]

, 2019
Glioblastomas (GBM) are highly infiltrated by myeloid-derived innate immune cells that contribute to the immunosuppressive nature of the brain tumor microenvironment (TME).
Gao, Peisong, Lal, Bachchu, Laterra, John, Lee, Richard S, Li, Jian Jian, Liu, Senquan, Lopez-Bertoni, Hernando, Ma, Ding, Wang, Shuyan, Wei, Shuang, Wilson, Mary Ann, Xia, Shuli, Ying, Mingyao, Zhan, Daqian, Zhang, Hao   +14 more
core   +2 more sources

Gab2 plays a carcinogenic role in ovarian cancer by regulating CrkII

Journal of Ovarian Research, 2023
Objective To detect the expression of Growth factor binding protein 2 associated binding protein 2 (Gab2) and CT10 regulator of kinase II (CrkII) in ovarian cancer and analyze their clinical significance.
Yi Yin, Li Zhang, Yong Li, Can Zhang, Aiqin He   +4 more
doaj   +1 more source

Diffusion Tensor Imaging for Assessment of Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer. [PDF]

, 2016
In this study, the prognostic significance of tumor metrics derived from diffusion tensor imaging (DTI) was evaluated in patients with locally advanced breast cancer undergoing neoadjuvant therapy.
Harnish, Roy, Hylton, Nola M, Li, Wen, Newitt, David C, Proctor, Evelyn, Shin, Hee Jung, Wilmes, Lisa J   +6 more
core   +1 more source

Macrophages in Tumor Microenvironments and the Progression of Tumors [PDF]

Clinical and Developmental Immunology, 2012
Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. Macrophages can be activated by a variety of stimuli and polarized to functionally different phenotypes.
Shi-Ming Yang, Ya-Ling Cao, Zhi-Ren Zhang, Mu-Han Lü, Ya-Han Fan, Ning-Bo Hao   +5 more
openaire   +3 more sources

RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

Journal of Translational Medicine, 2022
Background Targeting glutamine metabolism is previously indicated as a potential and attractive strategy for gastric cancer (GC) therapy. However, the underlying mechanisms responsible for the modification of glutamine metabolism in GC cells have not ...
Haofeng Liu, Qiu Xue, Hongzhou Cai, Xiaohui Jiang, Guangxin Cao, Tie Chen, Yuan Chen, Ding Wang   +7 more
doaj   +1 more source

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

Cellular & Molecular Immunology, 2020
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and immune checkpoint inhibitors (ICIs), have obtained durable clinical responses, but
Yuanyuan Zhang, Zemin Zhang
semanticscholar   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

Malaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson   +8 more
doaj   +1 more source