Results 181 to 190 of about 15,304,481 (401)

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

Science, 2013
Min Yu, A. Bardia, Ben S. Wittner, Shannon L. Stott, Malgorzata E. Smas, D. Ting, S. Isakoff, Jordan C. Ciciliano, Marissa N. Wells, Ajay M Shah, K. Concannon, M. C. Donaldson, L. Sequist, E. Brachtel, D. Sgroi, J. Baselga, Sridhar Ramaswamy, M. Toner, D. Haber, S. Maheswaran   +19 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Activation of Dendritic Cells That Cross-Present Tumor-Derived Antigen Licenses CD8+ CTL to Cause Tumor Eradication [PDF]

, 2004
Geertje J. D. van Mierlo, Zita F. H. M. Boonman, Hélène Dumortier, Annemieke Th. den Boer, Marieke F. Fransen, Jan Nouta, Ellen I. H. van der Voort, Rienk Offringa, René E. M. Toes, Cornelis J.M. Melief   +9 more
openalex   +1 more source

The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation [PDF]

, 2022
Eva Sum, Moritz Rapp, Harald Dürr, Alekhya Mazumdar, Pedro Romero, Christine Trumpfheller, Pablo Umaña   +6 more
openalex   +1 more source

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

Science, 2018
D. Pan, Aya Kobayashi, Aya Kobayashi, Peng Jiang, L. F. Andrade, Rong En Tay, Adrienne M. Luoma, Daphne M Tsoucas, Xintao Qiu, Klothilda Lim, P. Rao, Henry W. Long, Guocheng Yuan, John G Doench, Myles A. Brown, X. Liu, K. Wucherpfennig   +16 more
semanticscholar   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors [PDF]

, 2012
Anitha Shenoy, Robert C. Fisher, Elizabeth A. Butterworth, Liya Pi, Lung-Ji Chang, Henry D. Appelman, Myron Chang, Edward W. Scott, Emina H. Huang   +8 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Liquid biopsy: from discovery to clinical implementation

Molecular Oncology, 2021
Catherine Alix‐Panabières, Klaus Pantel   +1 more
doaj   +1 more source