Results 181 to 190 of about 15,400,316 (399)

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology

, 2016
James Che, Victor Yu, Manjima Dhar, Corinne Renier, Melissa Matsumoto, Kyra Heirich, Edward B. Garon, Jonathan W. Goldman, Jianyu Rao, George W. Sledge, Mark D. Pegram, Shruti Sheth, Stefanie S. Jeffrey, Rajan P. Kulkarni, Elodie Sollier, Dino Di Carlo   +15 more
openalex   +2 more sources

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

Science, 2018
D. Pan, Aya Kobayashi, Aya Kobayashi, Peng Jiang, L. F. Andrade, Rong En Tay, Adrienne M. Luoma, Daphne M Tsoucas, Xintao Qiu, Klothilda Lim, P. Rao, Henry W. Long, Guocheng Yuan, John G Doench, Myles A. Brown, X. Liu, K. Wucherpfennig   +16 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth

, 2011
Natasha Y. Frank, Tobias Schatton, Soo‐Jeong Kim, Qian Zhan, Brian J. Wilson, Jie Ma, Karim R. Saab, Veronika Osherov, Hans R. Widlund, Martin Gasser, Ana-Maria Waaga-Gasser, Thomas S. Kupper, Gëorge F. Murphy, Markus H. Frank   +13 more
openalex   +2 more sources

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

Proceedings of the National Academy of Sciences of the United States of America, 2002
Yoshiko Iwai, Masayoshi Ishida, Yoshimasa Tanaka, Taku Okazaki, T. Honjo, N. Minato   +5 more
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The chemopreventive agent α‐difluoromethylornithine blocks Ki‐ras–dependent tumor formation and specific gene expression in Caco‐2 cells [PDF]

, 2004
Natalia A. Ignatenko, Hui Zhang, George S. Watts, Bethany A. Skovan, David E. Stringer, Eugene W. Gerner   +5 more
openalex   +1 more source

Preoperative C-reactive protein is related with renal cell tumor dimension? Preliminary results [PDF]

, 2023
Adelina Miron, Viorel Jinga, George Daniel Rădăvoi, Tudor Marian Proca, Andreea Stan, Dragoş Puia, Cătălin Pricop   +6 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Fabrication of Red Blood Cell-Based Multimodal Theranostic Probes for Second Near-Infrared Window Fluorescence Imaging-Guided Tumor Surgery and Photodynamic Therapy

, 2019
Peiyuan Wang, Xuandong Wang, Qiang Luo, Yang Li, Xiaoxiao Lin, Lingling Fan, Yun Zhang, Jingfeng Liu, Xiaolong Liu   +8 more
openalex   +1 more source