Results 191 to 200 of about 2,987,261 (338)

Receptor-Mediated Internalization of L-Asparaginase into Tumor Cells Is Suppressed by Polyamines. [PDF]

Int J Mol Sci
Zlotnikov ID, Ezhov AA, Kudryashova EV.
europepmc   +1 more source

THE EFFECT OF ANTIBODY ON INTRACELLULAR VACCINIA VIRUS MULTIPLICATION IN THE EHRLICH ASCITES TUMOR CELLS

, 1959
Eiichi Furusawa, Kumao Toyoshima, Tadashi Miyagawa   +2 more
openalex   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

On the Relationship of Ehrlich Ascites Tumor Cells to Tsutsugamushi Disease Rickettsiae

, 1959
Reiji Yagi
openalex   +2 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Clinical significance and heterogeneity of circulating tumor cells and clusters in breast cancer subtypes. [PDF]

PeerJ
Hao L, Zheng L.
europepmc   +1 more source

Morphological Studies on Human Ascites Tumor Cells by Tissue culture

, 1959
Takakazu Asaka
openalex   +2 more sources

Cystic Lesions of Bone Resembling Giant Cell Tumors [PDF]

, 1962
T Hiertonn, E. Salén
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

New Kinase Inhibitors That Are Selectively Cytotoxic for Tumor Cells. [PDF]

Dokl Biochem Biophys
Skvortsov DA, Zhirkina IV, Ipatova DA, Pisarev AR, Malyshev AS, Ivanenkov YA, Kartsev VG, Dontsova OA.   +7 more
europepmc   +1 more source