Results 241 to 250 of about 2,987,261 (338)

CHROMOSOMAL ALTERATION AND THE DEVELOPMENT OF TUMORS XIII. KARYOTYPIC DIFFERENCE IN SOLID AND ASCITES TYPE TUMORS OF MOUSE PLASMA CELL NEOPLASM X5563, WITH SPECIAL REGARD TO THE SERUM ELECTROPHORETIC PATTERN OF GAMMA GLOBULIN

, 1966
Tosihide H. YOSIDA, Yoshinori Kurita, Kazuo Moriwaki   +2 more
openalex   +2 more sources

Tumor Cell Societies [PDF]

JNCI Journal of the National Cancer Institute, 1989
openaire   +3 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Editorial: Predictive and prognostic value of liquid biopsy biomarkers in metastatic cancers: from basic science, across high throughput profiling up to clinical practice

Frontiers in Oncology
Dorota Kwapisz, Patrycja Pawlikowska, Areti Strati   +2 more
doaj   +1 more source

A Dissociative Effect of Puromycin on the Pathway of Protein Synthesis by Ehrlich Ascites Tumor Cells

, 1962
M. Rabinovitz, Joyce M. Fisher
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts

Signal Transduction and Targeted Therapy
Marina Kolesnichenko, Claus Scheidereit
doaj   +1 more source

Characterization of Disseminated Tumor Cells (DTCs) in Patients with Triple-Negative Breast Cancer (TNBC). [PDF]

Cells
Eckardt A, Nel I, Weydandt L, Brochwitz E, Höhn AK, Winter K, Aktas B.   +6 more
europepmc   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Natural killer cells: the immune frontline against circulating tumor cells. [PDF]

J Exp Clin Cancer Res
Masmoudi D, Villalba M, Alix-Panabières C.   +2 more
europepmc   +1 more source