Results 261 to 270 of about 2,987,261 (338)

Precise photopharmacological eradication of metastatic tumor cells.

Dis Model Mech
Varady A, Grissenberger S, Wenninger-Weinzierl A, Poplimont H, Sturtzel C, Schmitner N, Gao L, Kimmel RA, Distel M.   +8 more
europepmc   +1 more source

NOX Family: Regulators of Reactive Oxygen Species Balance in Tumor Cells. [PDF]

FASEB J
Xiong B, Zhang Y, Liu S, Liao S, Zhou Z, He Q, Zhou Y.   +6 more
europepmc   +1 more source

Inhibition and Stimulation of the Biosynthesis of Protein and Nucleic Acid. II. Inhibition Sites of 4-Fluoro- and 4-Nitro-phenylalanines on the Incorporation of Phenylalanine into Proteins of Ehrlich Mouse Ascites Tumor Cells in vitro

, 1968
Osamu Tamemasa, Shoji Okada, Setsuo IWASAKI, Eiko Watanabe   +3 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Enhanced immunotherapy response in lung adenocarcinoma patients with COPD: insights into tumor cells and immune microenvironment characteristics. [PDF]

Cell Commun Signal
Huang Y, Liang B, Chen X, Li Z, Deng Y, Du J, Zhong Y, Lin X, Fu J, Xie J, Zhang X, Huang Z.   +11 more
europepmc   +1 more source

STUDIES ON THE REGULATION OF CERTAIN ESSENTIAL BIOSYNTHETIC SYSTEMS IN NORMAL AND CROWN-GALL TUMOR CELLS

, 1961
Henry N. Wood, Armin Braun
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells. [PDF]

Int J Mol Sci
Vargas C, Aguirre-Ducler A, Cereceda K, Quijada S, Escobar-Gómez N, Castillo RL, Escobar-Aguirre M.   +6 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source