Results 271 to 280 of about 15,304,481 (401)

SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions

Qing Deng, Priya Lakra, Panhong Gou, Haopeng Yang, Cem Meydan, Matthew Teater, Christopher R. Chin, Wenchao Zhang, Tommy Dinh, Usama Khamis Hussein, Xubin Li, Estela Rojas, Weiguang Liu, Patrick K. Reville, Atish Kizhakeyil, Darko Barišić, Sydney Parsons, Ashley Wilson, Jared Henderson, Brooks Scull, Channabasavaiah B. Gurumurthy, Francisco Vega, Amy Chadburn, Branko Cuglievan, Nader Kim El‐Mallawany, Carl E. Allen, Christopher E. Mason, Ari Melnick, Michael R. Green   +28 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Circulating tumor cells as predictive biomarkers in the risk stratification of DCIS: Evidence of early dissemination. [PDF]

Sci Adv
Nagpal N, Rupp B, Hong Y, Wagner J, Larson K, Balanoff C, Aripoli A, Huppe A, Winblad O, Peterson J, Hill M, Smith C, Fabian C, Godwin AK, Fields T, Wicha M, Behbod F, Nagrath S.   +17 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Detection of biogenic magnetic nanoparticles in rapidly dividing tumor cells by the nonlinear magnetization method. [PDF]

Front Bioeng Biotechnol
Milovanova MV, Gabashvili AN, Mochalova EN, Gurtovaya EO, Egorova IE, Dresviannikova AA, Griaznova OY, Nikitin PI.   +7 more
europepmc   +1 more source

Normalization of Tumor Microenvironment by Neem Leaf Glycoprotein Potentiates Effector T Cell Functions and Therapeutically Intervenes in the Growth of Mouse Sarcoma

, 2013
Subhasis Barik, Saptak Banerjee, Atanu Mallick, Kuntal Kanti Goswami, Soumyabrata Roy, Anamika Bose, Rathindranath Baral   +6 more
openalex   +2 more sources

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.

Journal of Clinical Investigation, 2008
P. Sonveaux, F. Végran, Thies Schroeder, M. Wergin, J. Verrax, Z. Rabbani, Christophe J. De Saedeleer, Kelly M. Kennedy, C. Diepart, B. Jordan, M. J. Kelley, B. Gallez, M. Wahl, O. Féron, M. Dewhirst   +14 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Size Matters: Small Circulating Tumor Cells Indicate Worse Therapy Response in Breast Cancer. [PDF]

MedComm (2020)
Wenta R, Muchlińska A, Suchodolska G, Senkus E, Żaczek A, Bednarz-Knoll N.   +5 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source