Results 281 to 290 of about 2,984,719 (362)

Identification of circulating tumor cells marker genes as prognostic signature in triple-negative breast cancer. [PDF]

Discov Oncol
Hu J, Zhang KM, Wang X.
europepmc   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Comparative analysis of circulating tumor cells in prostatic plexus and peripheral blood of patients undergoing prostatectomy. [PDF]

J Exp Clin Cancer Res
Emurlai G, Pose RM, Kalra N, Coith C, Lenz S, Tennstedt P, Graefen M, Werner S, Riethdorf S, Tilki D, Joosse SA, Pantel K.   +11 more
europepmc   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Fluorescent Probes to Image the K_Ca3.1 Channel in Tumor Cells. [PDF]

Pharmaceutics
Thale I, Naß E, Vinnenberg L, Todesca LM, Budde T, Maisuls I, Strassert CA, Schwab A, Wünsch B.   +8 more
europepmc   +1 more source

NONRANDOMNESS IN THE DISTRIBUTION OF CHROMOSOME ABERRATIONS INDUCED BY A RADIOMIMETIC CHEMICAL, 4-NITROQUINOLINE 1-OXIDE, IN TUMOR CELLS

, 1965
Yoshinori Kurita, Tosihide H. YOSIDA, Kazuo Moriwaki   +2 more
openalex   +2 more sources

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Dynamic single-cell metabolomics reveals cell-cell interaction between tumor cells and macrophages. [PDF]

Nat Commun
Zhang Y, Shi M, Li M, Qin S, Miao D, Bai Y.   +5 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Optimizing Detection of Circulating Tumor Cells in Breast Cancer: Unveiling New Markers for Clinical Applications. [PDF]

Int J Mol Sci
Mehtar A, Wechsler J, Desterke C, Giron-Michel J, Bouzidi A, Burlion A, Louache F, Kahia-Tani S, Uzan G, Naserian S.   +9 more
europepmc   +1 more source